Asenapine Transdermal Patch

377 interactions 1 explained in plain English 412 cited references
Also sold as: Secuado Secuado®
About Asenapine Transdermal Patch

Asenapine transdermal patches are used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Asenapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain… Read the full Asenapine Transdermal Patch drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Mesoridazine Metoclopramide Pimozide Piperaquine Bepridil
15 Contraindicated 276 Major 86 Moderate
All (377) Contraindicated (15) Major (276) Moderate (86)

Contraindicated

Asenapine Transdermal Patch Bepridil An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Bromopride Increased risk of extrapyramidal reactions Details Asenapine Transdermal Patch Cisapride Propulsid® Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Dronedarone Multaq Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Isocarboxazid Marplan An increased risk of CNS depression Details Asenapine Transdermal Patch Levoketoconazole Recorlev An increased risk of QT interval prolongation and an increased risk of torsade de pointes Details Asenapine Transdermal Patch Mesoridazine Increased risk of CNS depression and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Metoclopramide An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Asenapine Transdermal Patch Pimozide Increased risk of CNS depression and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Piperaquine An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Saquinavir An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sparfloxacin An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Terfenadine An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Thioridazine An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Ziprasidone Geodon An increased risk of QT interval prolongation and an increased risk of CNS depression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.