Atazanavir

179 interactions 13 explained in plain English

Also sold as: Reyataz

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Irinotecan Lipid Complex Injection Midazolam Nasal Spray Encorafenib Lovastatin Lurasidone Colchicine

18 Contraindicated 134 Major 27 Moderate

All (179) Contraindicated (18) Major (134) Moderate (27)

Moderate

Atazanavir Trospium / Xanomeline Cobenfy Explained Increased oral sensitive CYP3A4 substrate exposure and an increased risk on severity and frequency of sensitive CYP3A4 substrate-r... Details Atazanavir Abemaciclib Verzenio Explained Increased abemaciclib plasma concentration Details Atazanavir Acebutolol Sectral® An increased risk of PR interval prolongation Details Atazanavir Betaxolol Betoptic S An increased risk of PR interval prolongation Details Atazanavir Betaxolol Ophthalmic Betoptic® An increased risk of PR interval prolongation Details Atazanavir Canagliflozin Invokana Worsening glycemic control Details Atazanavir Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Atazanavir Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Atazanavir Dapsone Aczone An increased risk of hemolytic anemia and symptomatic hyperbilirubinemia Details Atazanavir Dapsone Topical Aczone An increased risk of hemolytic anemia and symptomatic hyperbilirubinemia Details Atazanavir Diazepam Nasal Spray Valtoco Increased diazePAM exposure Details Atazanavir Diazepam Rectal Diastat Increased diazePAM exposure Details Atazanavir Digoxin Cardoxin® Increased digoxin exposure Details Atazanavir Esmolol Brevibloc An increased risk of PR interval prolongation Details Atazanavir Estradiol Delestrogen An increase in exposure to the combination contraceptive Details Atazanavir Estradiol Topical Divigel An increase in exposure to the combination contraceptive Details Atazanavir Estradiol Transdermal Patch Alora® An increase in exposure to the combination contraceptive Details Atazanavir Everolimus Afinitor Increased everolimus exposure Details Atazanavir Guanfacine Intuniv Increased guanfacine exposure Details Atazanavir Labetalol Normodyne® An increased risk of PR interval prolongation Details Atazanavir Levonorgestrel After banger An increase in exposure to the combination contraceptive Details Atazanavir Levonorgestrel Intrauterine System Kyleena An increase in exposure to the combination contraceptive Details Atazanavir Linagliptin Tradjenta Worsening glycemic control Details Atazanavir Nadolol Corgard An increased risk of PR interval prolongation Details Atazanavir Nateglinide Starlix® Worsening glycemic control Details Atazanavir Nebivolol Bystolic An increased risk of PR interval prolongation Details Atazanavir Paricalcitol Zemplar Increased plasma concentrations of paricalcitol Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.