Azathioprine

Name: Azathioprine Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

219 interactions 2 explained in plain English 370 cited references

Also sold as: Azasan Azasan® Imuran Imuran®

About Azathioprine

Azathioprine is used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system) in people who received kidney transplants. It is also used to treat severe rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of f… Read the full Azathioprine drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Febuxostat Peginterferon Alfa-2A Injection Atovaquone Acarbose Adenovirus Vaccine Type 4, Live Adenovirus Vaccine Type 7, Live

1 Contraindicated 213 Major 5 Moderate

All (219) Contraindicated (1) Major (213) Moderate (5)

Contraindicated

Azathioprine Febuxostat Uloric Increased azaTHIOprine exposure and an increased risk of hepatotoxicity Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.