Betaxolol Ophthalmic

161 interactions 395 cited references
Also sold as: Betoptic® Betoptic® S
About Betaxolol Ophthalmic

Ophthalmic betaxolol is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Betaxolol is in a class of medications called beta blockers. It works by decreasing the pressure in the eye. Read the full Betaxolol Ophthalmic drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Moderate

Betaxolol Ophthalmic Ibuprofen Addaprin Reduced antihypertensive effect Details Betaxolol Ophthalmic Indomethacin Indocin Reduced antihypertensive effect Details Betaxolol Ophthalmic Insulin Aspart, Recombinant Fiasp Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Insulin Degludec Tresiba Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Insulin Detemir Levemir Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Insulin Glargine, Recombinant Basaglar Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Insulin Glulisine Apidra Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Insulin Human Inhaled Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Insulin Human Isophane (Nph) Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Insulin Human Regular Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Insulin Lispro, Recombinant Admelog Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Ketoprofen Actron® Reduced antihypertensive effect Details Betaxolol Ophthalmic Ketorolac Acular Reduced antihypertensive effect Details Betaxolol Ophthalmic Lidoflazine Hypotension, bradycardia, and AV conduction disturbances Details Betaxolol Ophthalmic Linagliptin Tradjenta Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Liraglutide Saxenda Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Lixisenatide Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Lornoxicam Reduced antihypertensive effect Details Betaxolol Ophthalmic Loxoprofen Reduced antihypertensive effect Details Betaxolol Ophthalmic Lumiracoxib Reduced antihypertensive effect Details Betaxolol Ophthalmic Ma Huang Reduced hypotensive effect of beta-adrenergic blockers Details Betaxolol Ophthalmic Meclofenamate Meclodium® Reduced antihypertensive effect Details Betaxolol Ophthalmic Mefenamic Acid Ponstel® Reduced antihypertensive effect Details Betaxolol Ophthalmic Meloxicam Alloxate Reduced antihypertensive effect Details Betaxolol Ophthalmic Metformin Fortamet® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Methacholine Impaired reversal of methacholine-caused bronchoconstriction Details Betaxolol Ophthalmic Methimazole Felanorm Altered metabolism of the beta-adrenergic blocker Details Betaxolol Ophthalmic Methyldopa Aldomet® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Betaxolol Ophthalmic Metildigoxin Increased risk of bradycardia and possible digitalis glycoside toxicity Details Betaxolol Ophthalmic Miglitol Glyset® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Morniflumate Reduced antihypertensive effect Details Betaxolol Ophthalmic Moxisylyte An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Ophthalmic Moxonidine Rebound hypertension Details Betaxolol Ophthalmic Nabumetone Relafen Reduced antihypertensive effect Details Betaxolol Ophthalmic Naproxen Aleve Reduced antihypertensive effect Details Betaxolol Ophthalmic Nateglinide Starlix® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Nepafenac Ilevro Reduced antihypertensive effect Details Betaxolol Ophthalmic Nifedipine Adalat® An increased risk of congestive heart failure, severe hypotension or exacerbation of angina Details Betaxolol Ophthalmic Niflumic Acid Reduced antihypertensive effect Details Betaxolol Ophthalmic Nimesulide Reduced antihypertensive effect Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.