Betaxolol Ophthalmic

161 interactions 395 cited references
Also sold as: Betoptic® Betoptic® S
About Betaxolol Ophthalmic

Ophthalmic betaxolol is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Betaxolol is in a class of medications called beta blockers. It works by decreasing the pressure in the eye. Read the full Betaxolol Ophthalmic drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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30 Major 131 Moderate
All (161) Major (30) Moderate (131)

Moderate

Betaxolol Ophthalmic Nimesulide Beta Cyclodextrin Reduced antihypertensive effect Details Betaxolol Ophthalmic Oxaprozin Coxanto Reduced antihypertensive effect Details Betaxolol Ophthalmic Oxyphenbutazone Reduced antihypertensive effect Details Betaxolol Ophthalmic Paltusotine Palsonify An increased risk of PR interval prolongation Details Betaxolol Ophthalmic Parecoxib Reduced antihypertensive effect Details Betaxolol Ophthalmic Phenoxybenzamine Dibenzyline An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Ophthalmic Phentolamine An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Ophthalmic Phenylbutazone Equi-Phar Reduced antihypertensive effect Details Betaxolol Ophthalmic Piketoprofen Reduced antihypertensive effect Details Betaxolol Ophthalmic Pioglitazone Actos Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Piroxicam Feldene Reduced antihypertensive effect Details Betaxolol Ophthalmic Pramlintide Symlin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Pranoprofen Reduced antihypertensive effect Details Betaxolol Ophthalmic Prazosin Minipress An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Ophthalmic Proglumetacin Reduced antihypertensive effect Details Betaxolol Ophthalmic Propyphenazone Reduced antihypertensive effect Details Betaxolol Ophthalmic Proquazone Reduced antihypertensive effect Details Betaxolol Ophthalmic Repaglinide Prandin® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Rofecoxib Reduced antihypertensive effect Details Betaxolol Ophthalmic Rosiglitazone Avandia® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Salicylic Acid Reduced antihypertensive effect Details Betaxolol Ophthalmic Salsalate Disalcid Reduced antihypertensive effect Details Betaxolol Ophthalmic Saxagliptin Onglyza Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Sitagliptin Brynovin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Sodium Salicylate Reduced antihypertensive effect Details Betaxolol Ophthalmic Sulindac Clinoril® Reduced antihypertensive effect Details Betaxolol Ophthalmic Tamsulosin Flomax An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Ophthalmic Tenoxicam Reduced antihypertensive effect Details Betaxolol Ophthalmic Terazosin Hytrin® An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Ophthalmic Tiaprofenic Acid Reduced antihypertensive effect Details Betaxolol Ophthalmic Tolazamide Tolinase® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Tolbutamide Orinase® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Tolfenamic Acid Reduced antihypertensive effect Details Betaxolol Ophthalmic Tolmetin Tolectin 600 Reduced antihypertensive effect Details Betaxolol Ophthalmic Tranylcypromine Parnate An increased risk of more pronounced bradycardia and postural hypotension Details Betaxolol Ophthalmic Trimazosin An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Ophthalmic Urapidil An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Ophthalmic Valdecoxib Reduced antihypertensive effect Details Betaxolol Ophthalmic Vildagliptin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ophthalmic Yohimbine Reduced beta-adrenergic blocker effectiveness Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.