Betaxolol

188 interactions 1 explained in plain English 395 cited references
Also sold as: Betoptic S Kerlone®
About Betaxolol

Betaxolol is a beta blocker used to control high blood pressure. Read the full Betaxolol drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Albuterol Oral Inhalation Albuterol Ceritinib Clonidine Crizotinib Darunavir
35 Major 153 Moderate
All (188) Major (35) Moderate (153)

Moderate

Betaxolol Nabumetone Relafen Reduced antihypertensive effect Details Betaxolol Naproxen Aleve Reduced antihypertensive effect Details Betaxolol Nateglinide Starlix® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Nepafenac Ilevro Reduced antihypertensive effect Details Betaxolol Nifedipine Adalat® An increased risk of congestive heart failure, severe hypotension or exacerbation of angina Details Betaxolol Niflumic Acid Reduced antihypertensive effect Details Betaxolol Nimesulide Reduced antihypertensive effect Details Betaxolol Nimesulide Beta Cyclodextrin Reduced antihypertensive effect Details Betaxolol Oxaprozin Coxanto Reduced antihypertensive effect Details Betaxolol Oxyphenbutazone Reduced antihypertensive effect Details Betaxolol Paltusotine Palsonify An increased risk of PR interval prolongation Details Betaxolol Parecoxib Reduced antihypertensive effect Details Betaxolol Phenoxybenzamine Dibenzyline An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Phentolamine An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Phenylbutazone Equi-Phar Reduced antihypertensive effect Details Betaxolol Piketoprofen Reduced antihypertensive effect Details Betaxolol Pioglitazone Actos Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Piroxicam Feldene Reduced antihypertensive effect Details Betaxolol Pramlintide Symlin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Pranoprofen Reduced antihypertensive effect Details Betaxolol Prazosin Minipress An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Proglumetacin Reduced antihypertensive effect Details Betaxolol Propyphenazone Reduced antihypertensive effect Details Betaxolol Proquazone Reduced antihypertensive effect Details Betaxolol Repaglinide Prandin® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Rofecoxib Reduced antihypertensive effect Details Betaxolol Rosiglitazone Avandia® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Salicylic Acid Reduced antihypertensive effect Details Betaxolol Salsalate Disalcid Reduced antihypertensive effect Details Betaxolol Saxagliptin Onglyza Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Sitagliptin Brynovin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Sodium Salicylate Reduced antihypertensive effect Details Betaxolol Sulindac Clinoril® Reduced antihypertensive effect Details Betaxolol Tamsulosin Flomax An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Tenoxicam Reduced antihypertensive effect Details Betaxolol Terazosin Hytrin® An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Tiaprofenic Acid Reduced antihypertensive effect Details Betaxolol Tolazamide Tolinase® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Tolbutamide Orinase® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Tolfenamic Acid Reduced antihypertensive effect Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.