Betaxolol

188 interactions 1 explained in plain English 395 cited references

Also sold as: Betoptic S Kerlone®

About Betaxolol

Betaxolol is a beta blocker used to control high blood pressure. Read the full Betaxolol drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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35 Major 153 Moderate

All (188) Major (35) Moderate (153)

Moderate

Betaxolol Tolmetin Tolectin 600 Reduced antihypertensive effect Details Betaxolol Tranylcypromine Parnate An increased risk of more pronounced bradycardia and postural hypotension Details Betaxolol Trimazosin An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Urapidil An exaggerated hypotensive response to the first dose of the alpha blocker Details Betaxolol Valdecoxib Reduced antihypertensive effect Details Betaxolol Vildagliptin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Yohimbine Reduced beta-adrenergic blocker effectiveness Details Betaxolol Zileuton Zyflo A significant increase in beta-adrenergic blockade Details Betaxolol Bromfenac Ophthalmic Bromday® Reduced antihypertensive effect Details Betaxolol Diclofenac Ophthalmic Voltaren® Eye Drops Reduced antihypertensive effect Details Betaxolol Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced antihypertensive effect Details Betaxolol Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced antihypertensive effect Details Betaxolol Diclofenac Transdermal Patch Flector Reduced antihypertensive effect Details Betaxolol Dulaglutide Injection Trulicity Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Exenatide Injection Bydureon Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Flurbiprofen Ophthalmic Ocufen Reduced antihypertensive effect Details Betaxolol Glucagon Injection Baqsimi A transient increase in pulse and blood pressure Details Betaxolol Glucagon Injection / Solution Baqsimi A transient increase in pulse and blood pressure Details Betaxolol Glucagon Nasal Powder Baqsimi A transient increase in pulse and blood pressure Details Betaxolol Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Insulin Detemir (Rdna Origin) Injection Levemir Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Insulin Glulisine (Rdna Origin) Injection Apidra Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Ketorolac Injection Acular Reduced antihypertensive effect Details Betaxolol Ketorolac Nasal Spray Sprix Reduced antihypertensive effect Details Betaxolol Ketorolac Ophthalmic Acular Reduced antihypertensive effect Details Betaxolol Liraglutide Injection Saxenda Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Lixisenatide Injection Adlyxin® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Betaxolol Meloxicam Injection Alloxate Reduced antihypertensive effect Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.