Bexarotene Topical

75 interactions 92 cited references
Also sold as: Targretin Targretin® Topical Gel
About Bexarotene Topical

Topical bexarotene is used to treat cutaneous T-cell lymphoma (CTCL, a type of skin cancer) that could not be treated with other medications. Bexarotene is in a class of medications called retinoids. It works by stopping the growth of cancer cells. Read the full Bexarotene Topical drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Measles Virus Vaccine, Live Mumps Virus Vaccine, Live Ranolazine Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Typhoid Vaccine
10 Contraindicated 54 Major 11 Moderate
All (75) Contraindicated (10) Major (54) Moderate (11)

Major

Bexarotene Topical Norgestrel Decreased contraceptive effectiveness Details Bexarotene Topical Oliceridine Olinvyk Reduced oliceridine exposure and reduced efficacy of oliceridine Details Bexarotene Topical Omadacycline Nuzyra An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Topical Oxytetracycline An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Topical Palovarotene Sohonos Increased risk of hypervitaminosis A Details Bexarotene Topical Rolitetracycline An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Topical Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details Bexarotene Topical Sarecycline Seysara An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Topical Segesterone Decreased contraceptive effectiveness Details Bexarotene Topical Tetracycline Achromycin V® An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Topical Tigecycline Tygacil An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Topical Tramadol ConZip Reduced traMADol exposure and reduced efficacy of traMADol Details Bexarotene Topical Ulipristal Ella Decreased contraceptive effectiveness Details Bexarotene Topical Voriconazole Vfend Reduced voriconazole exposure and an reduced efficacy of voriconazole Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.