Butabarbital

Name: Butabarbital Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

30 interactions 3 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acetaminophen And Codeine Nalbuphine Injection Morphine Injection Butorphanol Injection Butorphanol Nasal Spray Levonorgestrel

24 Major 6 Moderate

All (30) Major (24) Moderate (6)

Moderate

Butabarbital Capsaicin Arthricare for Women Moisturizing Increased or decreased effectiveness of barbiturates Details Butabarbital Capsaicin Topical Aspercreme Warming® Increased or decreased effectiveness of barbiturates Details Butabarbital Capsaicin Transdermal Patch Aspercreme Warming® Patch Increased or decreased effectiveness of barbiturates Details Butabarbital Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details Butabarbital Folic Acid Folacin Reduced folic acid exposure, reduced barbiturates exposure and reduced efficacy of barbiturate Details Butabarbital Ospemifene Osphena Decreased ospemifene exposure and efficacy Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.