Cabotegravir

Name: Cabotegravir Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

54 interactions 20 cited references

Also sold as: Apretude Vocabria Vocabria®

About Cabotegravir

Cabotegravir is used along with rilpivirine (Edurant) as a short-term treatment of human immunodeficiency virus type 1 (HIV-1) infection in certain adults and adolescents 12 years of age or older weighing at least 77 pounds (35 kg). Cabotegravir is used as a short-term prevention of human immunodeficiency virus type 1… Read the full Cabotegravir drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Carbamazepine Rifampin Rifabutin Phenytoin Phenobarbital Oxcarbazepine

7 Contraindicated 47 Major

All (54) Contraindicated (7) Major (47)

Major

Cabotegravir Tebipenem Pivoxil Increased tebipenem pivoxil exposure and an increased risk of tebipenem pivoxil-related adverse effects Details Cabotegravir Tenofovir Loss of virologic response and possible development of viral resistance Details Cabotegravir Tipranavir Aptivus Loss of virologic response and possible development of viral resistance Details Cabotegravir Zalcitabine Loss of virologic response and possible development of viral resistance Details Cabotegravir Zidovudine Retrovir Loss of virologic response and possible development of viral resistance Details Cabotegravir Enfuvirtide Injection Fuzeon Loss of virologic response and possible development of viral resistance Details Cabotegravir Ibalizumab-Uiyk Injection Trogarzo Loss of virologic response and possible development of viral resistance Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.