Ciprofloxacin

162 interactions 10 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Brexpiprazole Famotidine Metformin Galantamine Ifosfamide Injection Oxaliplatin Injection
133 Major 29 Moderate
All (162) Major (133) Moderate (29)

Major

Ciprofloxacin Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Ciprofloxacin Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details Ciprofloxacin Naloxegol Movantik Increased naloxegol exposure Details Ciprofloxacin Nateglinide Starlix® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ciprofloxacin Nifedipine Adalat® Increased NIFEdipine exposure Details Ciprofloxacin Octreotide Bynfezia An increased risk of QT interval prolongation and torsade de pointes Details Ciprofloxacin Octreotide Injection Bynfezia An increased risk of QT interval prolongation and torsade de pointes Details Ciprofloxacin Ofloxacin Floxin® An increased risk of fluoroquinolones-related adverse reactions and an increased risk of QT interval prolongation Details Ciprofloxacin Ofloxacin Ophthalmic Ocuflox An increased risk of fluoroquinolones-related adverse reactions and an increased risk of QT interval prolongation Details Ciprofloxacin Ofloxacin Otic Floxin® Otic An increased risk of fluoroquinolones-related adverse reactions and an increased risk of QT interval prolongation Details Ciprofloxacin Olaparib Lynparza Increased olaparib exposure Details Ciprofloxacin Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Ciprofloxacin Oxaliplatin Injection Eloxatin® Increased risk of QT-interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.