Clobetasol Topical

Name: Clobetasol Topical Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

29 interactions 229 cited references

Also sold as: Clobex® Cormax® Embeline® Olux Olux® Temovate® Tovet

About Clobetasol Topical

Clobetasol topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various scalp and skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body) and eczema (a skin disease that causes the skin to be dry and itchy and… Read the full Clobetasol Topical drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Desmopressin Mifepristone Aspirin Bemiparin Carbamazepine Cosyntropin

2 Contraindicated 18 Major 9 Moderate

All (29) Contraindicated (2) Major (18) Moderate (9)

Contraindicated

Clobetasol Topical Desmopressin DDAVP Increased risk of severe hyponatremia Details Clobetasol Topical Mifepristone Korlym An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.