Clobetasol Topical

29 interactions 229 cited references
Also sold as: Clobex® Cormax® Embeline® Olux Olux® Temovate® Tovet
About Clobetasol Topical

Clobetasol topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various scalp and skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body) and eczema (a skin disease that causes the skin to be dry and itchy and… Read the full Clobetasol Topical drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Clobetasol Topical Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Clobetasol Topical Bemiparin Increased risk of bleeding Details Clobetasol Topical Carbamazepine Carbatrol Reduced corticosteroids exposure and reduced efficacy of corticosteroids Details Clobetasol Topical Cosyntropin False elevations of plasma cortisol levels Details Clobetasol Topical Ethinyl Estradiol Increased corticosteroid exposure Details Clobetasol Topical Fosphenytoin Cerebyx Reduced corticosteroid exposure Details Clobetasol Topical Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Clobetasol Topical Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Clobetasol Topical Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Clobetasol Topical Lutetium Lu 177 Dotatate Decreased lutetium Lu 177 dotatate efficacy Details Clobetasol Topical Macimorelin False-positive or false-negative adult growth hormone deficiency diagnosis Details Clobetasol Topical Nadroparin Increased risk of bleeding Details Clobetasol Topical Phenytoin Dilantin Reduced corticosteroid exposure Details Clobetasol Topical Rabies Vaccine Imovax An inadequate immunological response to the vaccine, an increased risk of altered immunocompetence and reduced immune response to... Details Clobetasol Topical Relacorilant Lifyorli Reduced relacorilant exposure and reduced efficacy of relacorilant, reduced glucocorticoids exposure and reduced efficacy of gluco... Details Clobetasol Topical Sargramostim Leukine Increased myeloproliferative effects of sargramostim Details Clobetasol Topical Somatrogon-Ghla Reduced serum cortisol exposure, an increased risk of central (secondary) hypoadrenalism and attenuated growth-promoting effects o... Details Clobetasol Topical Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details

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