Cyclosporine Ophthalmic
545 interactions 1,631 cited referencesOphthalmic cyclosporine is used to increase tear production in people with dry eye disease. Cyclosporine is in a class of medications called immunomodulators. It works by decreasing swelling in the eye to allow for tear production. Read the full Cyclosporine Ophthalmic drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Moderate
Cyclosporine Ophthalmic Imipenem Neurotoxicity (mental confusion, agitation, tremor) Details Cyclosporine Ophthalmic Josamycin An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Kanamycin Renal dysfunction or nephrotoxicity Details Cyclosporine Ophthalmic Kratom Increased CYP3A substrate exposure Details Cyclosporine Ophthalmic Levacetylleucine Aqneursa Increased P-gp inhibitor exposure and an increased risk of P-gp substrate-related adverse reactions Details Cyclosporine Ophthalmic Lumefantrine Increased artemether/lumefantrine exposure and an increased risk of potentiated QT prolongation Details Cyclosporine Ophthalmic Mavacamten Camzyos Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Cyclosporine Ophthalmic Methyltestosterone An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Metreleptin Altered exposure to cycloSPORINE Details Cyclosporine Ophthalmic Metronidazole Flagyl An increased risk of cycloSPORINE toxicity (nephrotoxicity, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Miconazole Aloe Vesta Antifungal An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Midazolam Decreased midazolam clearance and increased midazolam plasma concentrations Details Cyclosporine Ophthalmic Miokamycin An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Nalidixic Acid Increased cycloSPORINE serum concentrations and risk of toxicity Details Cyclosporine Ophthalmic Neomycin Renal dysfunction or nephrotoxicity Details Cyclosporine Ophthalmic Netilmicin Renal dysfunction or nephrotoxicity Details Cyclosporine Ophthalmic Nilotinib Increased exposure of cycloSPORINE and nilotinib Details Cyclosporine Ophthalmic Norfloxacin Nephrotoxicity (oliguria, tachycardia, dyspnea) Details Cyclosporine Ophthalmic Oxypurinol Increased cycloSPORINE exposure Details Cyclosporine Ophthalmic Pasireotide Signifor Decreased cycloSPORINE exposure Details Cyclosporine Ophthalmic Pentopril Acute renal failure Details Cyclosporine Ophthalmic Prednisolone Flo-Pred® An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) and symptoms of steroid excess Details Cyclosporine Ophthalmic Prednisone Deltasone An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) and symptoms of corticosteroid excess (e... Details Cyclosporine Ophthalmic Pristinamycin An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Probucol Decreased cycloSPORINE concentrations Details Cyclosporine Ophthalmic Quercetin Reduced cycloSPORINE effectiveness Details Cyclosporine Ophthalmic Quinupristin Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Rabeprazole Aciphex Increased cycloSPORINE exposure Details Cyclosporine Ophthalmic Repaglinide Prandin® Increased repaglinide plasma concentrations Details Cyclosporine Ophthalmic Rilonacept Altered cycloSPORINE plasma concentrations Details Cyclosporine Ophthalmic Rilzabrutinib Wayrilz Increased P-gp substrate with NTI exposure and an increased risk of P-gp substrate with NTI-related adverse reactions Details Cyclosporine Ophthalmic Seladelpar Increased seladelpar exposure Details Cyclosporine Ophthalmic Sevelamer RenaGel Reduced efficacy of oral cyclosporine Details Cyclosporine Ophthalmic Sparsentan Filspari Increased sparsentan exposure and an increased cycloSPORINE exposure Details Cyclosporine Ophthalmic Stanozolol An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Streptomycin Renal dysfunction or nephrotoxicity Details Cyclosporine Ophthalmic Sulfadiazine Microsulfon® Decreased cycloSPORINE effectiveness Details Cyclosporine Ophthalmic Sulfasalazine Azulfidine Loss of cycloSPORINE efficacy Details Cyclosporine Ophthalmic Tenofovir Alafenamide Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure Details Cyclosporine Ophthalmic Tenofovir Disoproxil Fumarate Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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