Cyclosporine Ophthalmic
545 interactions 1,631 cited referencesOphthalmic cyclosporine is used to increase tear production in people with dry eye disease. Cyclosporine is in a class of medications called immunomodulators. It works by decreasing swelling in the eye to allow for tear production. Read the full Cyclosporine Ophthalmic drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Cyclosporine Ophthalmic Caspofungin Increased plasma levels of caspofungin and increased risk of hepatic enzyme elevations Details Cyclosporine Ophthalmic Celecoxib Celebrex An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ophthalmic Cenobamate Xcopri Reduced cycloSPORINE exposure Details Cyclosporine Ophthalmic Ceritinib Zykadia Increased exposure of CYP3A substrate Details Cyclosporine Ophthalmic Cerivastatin An increased risk of myopathy or rhabdomyolysis Details Cyclosporine Ophthalmic Cholera Vaccine, Live An inadequate immunological response to the vaccine, increased risk of disseminated infection with live vaccines and reduced effic... Details Cyclosporine Ophthalmic Cholic Acid Exacerbation of bile salt accumulation in the liver; increased clinical symptoms Details Cyclosporine Ophthalmic Choline Salicylate An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ophthalmic Cimetidine Tagamet An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Ciprofibrate Increased risk of renal dysfunction Details Cyclosporine Ophthalmic Ciprofloxacin Increased risk of renal dysfunction and an increased cycloSPORINE exposure Details Cyclosporine Ophthalmic Clarithromycin Biaxin Increased cycloSPORINE exposure Details Cyclosporine Ophthalmic Clofazimine Increased cycloSPORINE exposure Details Cyclosporine Ophthalmic Clofibrate Increased risk of renal dysfunction Details Cyclosporine Ophthalmic Clomipramine Anafranil Increased risk of seizures Details Cyclosporine Ophthalmic Clonixin An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ophthalmic Clozapine Clozaril Increased cloZAPine exposure Details Cyclosporine Ophthalmic Cobicistat Tybost Increased cycloSPORINE exposure and an increased cobicistat exposure Details Cyclosporine Ophthalmic Codeine Tuzistra XR® (as a combination product containing Chlorpheniramine, Codeine) Increased codeine and morphine exposure Details Cyclosporine Ophthalmic Conivaptan Vaprisol Increased CYP3A substrate exposure Details Cyclosporine Ophthalmic Crizotinib Xalkori Increased cycloSPORINE exposure Details Cyclosporine Ophthalmic Cyclophosphamide Cytoxan® Decreased serum cycloSPORINE concentration Details Cyclosporine Ophthalmic Dabigatran Etexilate Increased dabigatran exposure Details Cyclosporine Ophthalmic Dabrafenib Tafinlar Reduced sensitive CYP3A4 substrate exposure Details Cyclosporine Ophthalmic Daclatasvir Daklinza® Increased cycloSPORINE exposure Details Cyclosporine Ophthalmic Danicopan Voydeya Increased P-gp substrate exposure Details Cyclosporine Ophthalmic Daridorexant Increased daridorexant and cycloSPORINE exposure Details Cyclosporine Ophthalmic Darunavir Increased cycloSPORINE exposure and an increased darunavir exposure Details Cyclosporine Ophthalmic Dasabuvir Increased cycloSPORINE concentrations; increased dasabuvir concentrations Details Cyclosporine Ophthalmic Deflazacort Emflaza Increased exposure to active metabolite of deflazacort Details Cyclosporine Ophthalmic Delavirdine Rescriptor® Increased cycloSPORINE exposure Details Cyclosporine Ophthalmic Dengue Tetravalent Vaccine, Live An inadequate immunological response to the vaccine, increased risk of disseminated infection with live vaccines and reduced effic... Details Cyclosporine Ophthalmic Desogestrel Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Deutivacaftor Increased exposure to P-gp substrates and increased risk of P-gp substrates-related adverse effects Details Cyclosporine Ophthalmic Dexamethasone Reduced cycloSPORINE exposure Details Cyclosporine Ophthalmic Dexibuprofen An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ophthalmic Dexketoprofen An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ophthalmic Diclofenac Aleve Arthritis Pain An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ophthalmic Dienogest Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ophthalmic Diflunisal Dolobid An increased risk of cycloSPORINE nephrotoxicity DetailsNo interactions on this page match that filter — try the next page or clear the filter.
Check another drug
Still have questions about this combination?
Every question gets a real answer from a licensed pharmacist — free, and usually within a day.
Ask the pharmacist