Dabigatran

284 interactions 383 cited references
Also sold as: Pradaxa®
About Dabigatran

Dabigatran is a direct thrombin inhibitor anticoagulant used to treat blood clots and prevent strokes in patients with irregular heartbeats. Read the full Dabigatran drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Dabigatran Eptifibatide Increased risk of bleeding Details Dabigatran Erythromycin Erythrocin Stearate Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Escitalopram Lexapro An increased risk of bleeding Details Dabigatran Etodolac Lodine An increased risk of bleeding Details Dabigatran Etofenamate An increased risk of bleeding Details Dabigatran Etoricoxib An increased risk of bleeding Details Dabigatran Felbinac An increased risk of bleeding Details Dabigatran Felodipine Plendil® Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Fenoprofen Fenopron An increased risk of bleeding Details Dabigatran Fepradinol An increased risk of bleeding Details Dabigatran Feprazone An increased risk of bleeding Details Dabigatran Flibanserin Addyi Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Floctafenine An increased risk of bleeding Details Dabigatran Flufenamic Acid An increased risk of bleeding Details Dabigatran Fluoxetine RECONCILE An increased risk of bleeding Details Dabigatran Flurbiprofen Ansaid An increased risk of bleeding Details Dabigatran Fluvoxamine Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Fondaparinux Arixtra An increased risk of bleeding Details Dabigatran Fosphenytoin Cerebyx Reduced dabigatran exposure Details Dabigatran Fostamatinib Tavalisse Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Glecaprevir Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Heparin An increased risk of bleeding Details Dabigatran Ibrexafungerp Brexafemme Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Ibrutinib Imbruvica Increased risk of bleeding Details Dabigatran Ibuprofen Addaprin An increased risk of bleeding Details Dabigatran Iloprost Aurlumyn Increased risk of bleeding Details Dabigatran Imatinib Gleevec Increased dabigatran etexilate exposure Details Dabigatran Indinavir Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Indomethacin Indocin An increased risk of bleeding Details Dabigatran Inotersen Increased risk of bleeding Details Dabigatran Isavuconazole Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Isavuconazonium Cresemba Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Istradefylline Nourianz Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Itraconazole Sporanox Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Ivacaftor Kalydeco Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Ketoconazole Extina Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Ketoprofen Actron® An increased risk of bleeding Details Dabigatran Ketorolac Acular An increased risk of bleeding Details Dabigatran Lapatinib Tykerb Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Lecanemab-Irmb An increased risk of amyloid related imaging abnormalities (ARIA), or intracerebral hemorrhage Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.