Dabigatran

284 interactions 383 cited references
Also sold as: Pradaxa®
About Dabigatran

Dabigatran is a direct thrombin inhibitor anticoagulant used to treat blood clots and prevent strokes in patients with irregular heartbeats. Read the full Dabigatran drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Dabigatran Lenacapavir Sunlenca Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Lepirudin An increased risk of bleeding Details Dabigatran Levetiracetam Elepsia Decreased dabigatran exposure and possible subtherapeutic anticoagulation which could lead to a thrombotic event Details Dabigatran Levomilnacipran An increased risk of bleeding Details Dabigatran Lonafarnib Zokinvy Increased dabigatran exposure Details Dabigatran Lorlatinib Lorbrena Reduced dabigatran exposure, reduced efficacy of dabigatran and an increased risk of thrombosis Details Dabigatran Lornoxicam An increased risk of bleeding Details Dabigatran Loxoprofen An increased risk of bleeding Details Dabigatran Lumiracoxib An increased risk of bleeding Details Dabigatran Maribavir Livtencity Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Meclofenamate Meclodium® An increased risk of bleeding Details Dabigatran Mefenamic Acid Ponstel® An increased risk of bleeding Details Dabigatran Meloxicam Alloxate An increased risk of bleeding Details Dabigatran Melphalan Alkeran An increased risk of bleeding Details Dabigatran Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Dabigatran Mibefradil Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Mifepristone Korlym Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Milnacipran Savella An increased risk of bleeding Details Dabigatran Minocycline Amzeeq An increased risk of bleeding Details Dabigatran Mirabegron Myrbetriq Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Morniflumate An increased risk of bleeding Details Dabigatran Nabumetone Relafen An increased risk of bleeding Details Dabigatran Nadroparin An increased risk of bleeding Details Dabigatran Naproxen Aleve An increased risk of bleeding Details Dabigatran Nefazodone Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Nelfinavir Viracept Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Nepafenac Ilevro An increased risk of bleeding Details Dabigatran Neratinib Nerlynx Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Nifedipine Adalat® Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Niflumic Acid An increased risk of bleeding Details Dabigatran Nimesulide An increased risk of bleeding Details Dabigatran Nimesulide Beta Cyclodextrin An increased risk of bleeding Details Dabigatran Nintedanib Ofev Increased risk of bleeding Details Dabigatran Nirmatrelvir Increased dabigatran exposure and increased risk of bleeding Details Dabigatran Omadacycline Nuzyra Increased risk of bleeding Details Dabigatran Orlistat Alli An increased risk of bleeding Details Dabigatran Osimertinib Tagrisso Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Oxaliplatin Increased risk of bleeding Details Dabigatran Oxaprozin Coxanto An increased risk of bleeding Details Dabigatran Oxyphenbutazone An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.