Dacomitinib

Name: Dacomitinib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

56 interactions 1 explained in plain English 55 cited references

Also sold as: Vizimpro Vizimpro®

About Dacomitinib

Dacomitinib is used to treat a certain type of non-small-cell lung cancer (NSCLC) that has spread to other parts of the body. Dacomitinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the sprea… Read the full Dacomitinib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mumps Virus Vaccine, Live Dengue Tetravalent Vaccine, Live Measles Virus Vaccine, Live Pimozide Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine

10 Contraindicated 43 Major 3 Moderate

All (56) Contraindicated (10) Major (43) Moderate (3)

Major

Dacomitinib Valbenazine Ingrezza Increased valbenazine exposure and its active metabolite and an increased risk of valbenazine and its active metabolite-related ad... Details Dacomitinib Vortioxetine Trintellix Increased vortioxetine exposure Details Dacomitinib Esomeprazole Injection Nexium Reduced dacomitinib exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.