Dalfopristin

20 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Simvastatin Atorvastatin Fluvastatin Lovastatin Nifedipine
5 Major 15 Moderate
All (20) Major (5) Moderate (15)

Moderate

Dalfopristin Alfuzosin UroXatral An increase in alfuzosin exposure Details Dalfopristin Cyclosporine Injection Atopica Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Dalfopristin Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Dalfopristin Diazepam Nasal Spray Valtoco An increased risk of diazepam toxicity (excessive sedation, confusion) Details Dalfopristin Diazepam Rectal Diastat An increased risk of diazepam toxicity (excessive sedation, confusion) Details Dalfopristin Digoxin Cardoxin® Increased digoxin levels and digoxin toxicity (nausea, vomiting, arrhythmias) Details Dalfopristin Disopyramide Norpace An increased risk of disopyramide toxicity (cardiac arrhythmias, hypotension, syncope) Details Dalfopristin Felodipine Plendil® An increased risk of felodipine toxicity (dizziness, hypotension, flushing, headache, peripheral edema) Details Dalfopristin Isradipine DynaCirc® An increased risk of isradipine toxicity (dizziness, hypotension, flushing, headache, peripheral edema) Details Dalfopristin Midazolam Nasal Spray Nayzilam An increased risk of midazolam toxicity (excessive sedation, confusion) Details Dalfopristin Midazolam Injection Nayzilam An increased risk of midazolam toxicity (excessive sedation, confusion) Details Dalfopristin Nevirapine Viramune Increased nevirapine serum concentrations Details Dalfopristin Nicardipine Cardene An increased risk of niCARdipine toxicity (dizziness, hypotension, flushing, headache, peripheral edema) Details Dalfopristin Nimodipine Nimotop An increased risk of nimodipine toxicity (dizziness, headache, flushing, peripheral edema) Details Dalfopristin Nisoldipine Sular An increased risk of nisoldipine toxicity (dizziness, headache, flushing, peripheral edema) Details

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