Deflazacort

228 interactions 335 cited references
Also sold as: Emflaza Emflaza® Jaythari Kymbee Pyquvi
About Deflazacort

Deflazacort is used to treat Duchenne muscular dystrophy (DMD; a progressive disease in which the muscles do not function properly) in adults and children 2 years of age and older. Deflazacort is in a class of medications called corticosteroids. It works by reducing inflammation (swelling) and by changing the way the i… Read the full Deflazacort drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Deflazacort Lornoxicam Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Loxoprofen Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Lumacaftor Decreased exposure to active metabolite of deflazacort Details Deflazacort Lumiracoxib Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Lutetium Lu 177 Dotatate Decreased lutetium Lu 177 dotatate efficacy Details Deflazacort Macimorelin False-positive or false-negative adult growth hormone deficiency diagnosis Details Deflazacort Meclofenamate Meclodium® Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Mefenamic Acid Ponstel® Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Meloxicam Alloxate Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Mitotane Lysodren Decreased exposure to active metabolite of deflazacort Details Deflazacort Modafinil Provigil Decreased exposure to active metabolite of deflazacort Details Deflazacort Morniflumate Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Moxifloxacin Avelox An increased risk of tendon rupture Details Deflazacort Nabumetone Relafen Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Nadifloxacin An increased risk of tendon rupture Details Deflazacort Nadroparin Increased risk of bleeding Details Deflazacort Nafcillin Decreased exposure to active metabolite of deflazacort Details Deflazacort Naproxen Aleve Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Nefazodone Increased exposure to active metabolite of deflazacort Details Deflazacort Nelfinavir Viracept Increased exposure to active metabolite of deflazacort Details Deflazacort Nepafenac Ilevro Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Niflumic Acid Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Nilotinib Increased exposure to active metabolite of deflazacort Details Deflazacort Nimesulide Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Nimesulide Beta Cyclodextrin Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Nirmatrelvir Increased corticosteroid exposure Details Deflazacort Norfloxacin An increased risk of tendon rupture Details Deflazacort Ofloxacin Floxin® An increased risk of tendon rupture Details Deflazacort Omaveloxolone Skyclarys Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Deflazacort Oxaprozin Coxanto Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Oxyphenbutazone Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Parecoxib Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Pazufloxacin An increased risk of tendon rupture Details Deflazacort Pefloxacin An increased risk of tendon rupture Details Deflazacort Phenobarbital Fidoquel Decreased exposure to active metabolite of deflazacort Details Deflazacort Phenylbutazone Equi-Phar Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Phenytoin Dilantin Decreased exposure to active metabolite of deflazacort Details Deflazacort Piketoprofen Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Piroxicam Feldene Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Posaconazole Noxafil Increased exposure to active metabolite of deflazacort Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.