Deflazacort

228 interactions 335 cited references
Also sold as: Emflaza Emflaza® Jaythari Kymbee Pyquvi
About Deflazacort

Deflazacort is used to treat Duchenne muscular dystrophy (DMD; a progressive disease in which the muscles do not function properly) in adults and children 2 years of age and older. Deflazacort is in a class of medications called corticosteroids. It works by reducing inflammation (swelling) and by changing the way the i… Read the full Deflazacort drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Deflazacort Aldesleukin Proleukin Reduced antitumor effectiveness Details Deflazacort Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Deflazacort Aspirin Rectal Aspirin An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Deflazacort Besifloxacin Ophthalmic Besivance An increased risk of tendon rupture Details Deflazacort Bromfenac Ophthalmic Bromday® Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Cyclosporine Injection Atopica Increased exposure to active metabolite of deflazacort Details Deflazacort Cyclosporine Ophthalmic Cequa Increased exposure to active metabolite of deflazacort Details Deflazacort Aceclofenac Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Acemetacin Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Amtolmetin Guacil Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Apalutamide Erleada Reduced CYP3A4 substrate exposure Details Deflazacort Aprepitant Aponvie Increased exposure to active metabolite of deflazacort Details Deflazacort Atazanavir Reyataz Increased exposure to active metabolite of deflazacort Details Deflazacort Avacopan Tavneos Increased CYP3A4 substrate exposure Details Deflazacort Balofloxacin An increased risk of tendon rupture Details Deflazacort Bemiparin Increased risk of bleeding Details Deflazacort Besifloxacin An increased risk of tendon rupture Details Deflazacort Boceprevir Increased exposure to active metabolite of deflazacort Details Deflazacort Bosentan Decreased exposure to active metabolite of deflazacort Details Deflazacort Bromfenac Bromsite Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Bufexamac Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Bupropion Aplenzin Lowering of the seizure threshold Details Deflazacort Carbamazepine Carbatrol Decreased exposure to active metabolite of deflazacort Details Deflazacort Celecoxib Celebrex Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Choline Salicylate Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Ciprofloxacin An increased risk of tendon rupture Details Deflazacort Clarithromycin Biaxin Increased exposure to active metabolite of deflazacort Details Deflazacort Clonixin Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Cobicistat Tybost Increased exposure to active metabolite of deflazacort Details Deflazacort Conivaptan Vaprisol Increased exposure to active metabolite of deflazacort Details Deflazacort Cosyntropin False elevations of plasma cortisol levels Details Deflazacort Crizotinib Xalkori Increased exposure to active metabolite of deflazacort Details Deflazacort Cyclosporine Atopica Increased exposure to active metabolite of deflazacort Details Deflazacort Dexibuprofen Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Dexketoprofen Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Diclofenac Aleve Arthritis Pain Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Diflunisal Dolobid Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Diltiazem Cardizem Increased exposure to active metabolite of deflazacort Details Deflazacort Dipyrone Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Dronedarone Multaq Increased exposure to active metabolite of deflazacort Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.