Deflazacort

228 interactions 335 cited references
Also sold as: Emflaza Emflaza® Jaythari Kymbee Pyquvi
About Deflazacort

Deflazacort is used to treat Duchenne muscular dystrophy (DMD; a progressive disease in which the muscles do not function properly) in adults and children 2 years of age and older. Deflazacort is in a class of medications called corticosteroids. It works by reducing inflammation (swelling) and by changing the way the i… Read the full Deflazacort drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Desmopressin Desmopressin Nasal Ensitrelvir Mifepristone Ofloxacin Otic Aprepitant
4 Contraindicated 172 Major 51 Moderate 1 Minor
All (228) Contraindicated (4) Major (172) Moderate (51) Minor (1)

Moderate

Deflazacort Auranofin Ridaura Increased risk of auranofin-related adverse effects Details Deflazacort Adenovirus Vaccine Type 4, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Adenovirus Vaccine Type 7, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Aluminum Carbonate, Basic Decreased deflazacort effectiveness Details Deflazacort Aluminum Hydroxide AlternaGEL® Decreased deflazacort effectiveness Details Deflazacort Aluminum Phosphate Decreased deflazacort effectiveness Details Deflazacort Artemether Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Deflazacort Bacillus Of Calmette And Guerin Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Calcium Carbonate Alka-Mints Decreased deflazacort effectiveness Details Deflazacort Cholera Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Dengue Tetravalent Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Dihydroxyaluminum Aminoacetate Decreased deflazacort effectiveness Details Deflazacort Dihydroxyaluminum Sodium Carbonate Decreased deflazacort effectiveness Details Deflazacort Ebola Zaire Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Echinacea Decreased effectiveness of corticosteroids Details Deflazacort Gallium Ga 68 Dotatate Increased risk of false negative imaging Details Deflazacort Haemophilus B Vaccine An inadequate immunological response to the vaccine Details Deflazacort Hepatitis A Vaccine, Inactivated An inadequate immunological response to the vaccine Details Deflazacort Indapamide An increased risk of hypokalemia Details Deflazacort Influenza Virus Vaccine An inadequate immunological response to the vaccine Details Deflazacort Influenza Virus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Insulin Afrezza Reduced blood glucose lowering effect of insulin Details Deflazacort Insulin Lispro, Recombinant Admelog May decrease blood glucose lowering effect of insulin lispro Details Deflazacort Kratom Increased CYP3A substrate exposure Details Deflazacort Magaldrate Decreased deflazacort effectiveness Details Deflazacort Magnesium Carbonate Decreased deflazacort effectiveness Details Deflazacort Magnesium Hydroxide Almacone® (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone) Decreased deflazacort effectiveness Details Deflazacort Magnesium Oxide Mag-Ox 400 Decreased deflazacort effectiveness Details Deflazacort Magnesium Trisilicate Decreased deflazacort effectiveness Details Deflazacort Mavacamten Camzyos Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Deflazacort Measles Virus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Meningococcal Vaccine An inadequate immunological response to the vaccine Details Deflazacort Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details Deflazacort Mumps Virus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Olodaterol Striverdi An increased risk of hypokalemia Details Deflazacort Pneumococcal Vaccine An inadequate immunological response to the vaccine Details Deflazacort Pneumococcal Vaccine, Diphtheria Conjugate An inadequate immunological response to the vaccine Details Deflazacort Pneumococcal Vaccine Polyvalent An inadequate immunological response to the vaccine Details Deflazacort Poliovirus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Deflazacort Rilzabrutinib Wayrilz Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.