Deflazacort

Name: Deflazacort Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

228 interactions 335 cited references

Also sold as: Emflaza Emflaza® Jaythari Kymbee Pyquvi

About Deflazacort

Deflazacort is used to treat Duchenne muscular dystrophy (DMD; a progressive disease in which the muscles do not function properly) in adults and children 2 years of age and older. Deflazacort is in a class of medications called corticosteroids. It works by reducing inflammation (swelling) and by changing the way the i… Read the full Deflazacort drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Desmopressin Desmopressin Nasal Ensitrelvir Mifepristone Ofloxacin Otic Aprepitant

4 Contraindicated 172 Major 51 Moderate 1 Minor

All (228) Contraindicated (4) Major (172) Moderate (51) Minor (1)

Major

Deflazacort Ketoconazole Topical Extina® Foam Increased exposure to active metabolite of deflazacort Details Deflazacort Ketorolac Injection Acular Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Ketorolac Nasal Spray Sprix Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Ketorolac Ophthalmic Acular Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Letermovir Injection Prevymis Increased exposure to active metabolite of deflazacort Details Deflazacort Levofloxacin Injection Levaquin An increased risk of tendon rupture Details Deflazacort Meloxicam Injection Alloxate Increased risk of gastrointestinal ulcer or bleeding Details Deflazacort Moxifloxacin Injection Avelox An increased risk of tendon rupture Details Deflazacort Moxifloxacin Ophthalmic Moxeza® An increased risk of tendon rupture Details Deflazacort Nafcillin Injection Unipen® Injection Decreased exposure to active metabolite of deflazacort Details Deflazacort Ofloxacin Ophthalmic Ocuflox An increased risk of tendon rupture Details Deflazacort Ofloxacin Otic Floxin® Otic An increased risk of tendon rupture Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.