Demeclocycline

Name: Demeclocycline Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

63 interactions 111 cited references

Also sold as: Declomycin®

About Demeclocycline

Demeclocycline is used to treat infections caused by bacteria includingpneumonia and other respiratory tract infections;; certain infections of the skin, eye, lymphatic, intestinal, genital, and urinary systems; and certain other infections that are spread by ticks, lice, mites, and infected animals. It is also used al… Read the full Demeclocycline drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acitretin Bacampicillin Penicillin G Benzathine Injection Penicillin V Potassium Dicloxacillin Cloxacillin

1 Contraindicated 39 Major 23 Moderate

All (63) Contraindicated (1) Major (39) Moderate (23)

Contraindicated

Demeclocycline Acitretin Soriatane® An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.