Digoxin
453 interactions 2 explained in plain English 980 cited referencesDigoxin is a cardiac glycoside used to treat heart failure and abnormal heart rhythms by strengthening the heart's contractions and slowing heart rate. Read the full Digoxin drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Digoxin Apalutamide Erleada Reduced P-gp substrates exposure Details Digoxin Aranidipine An increased risk of bradycardia and an increased risk of complete heart block Details Digoxin Asunaprevir Increased digoxin exposure Details Digoxin Azilsartan Medoxomil Edarbi An increased digoxin exposure Details Digoxin Bemetizide Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Bendroflumethiazide Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Benzthiazide Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Bepridil An increased risk of bradycardia and an increased risk of complete heart block Details Digoxin Berotralstat Orladeyo Increased P-gp substrate exposure Details Digoxin Boceprevir Increased digoxin exposure Details Digoxin Bromfenac Bromsite Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Bufexamac Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Bupropion Aplenzin Reduced digoxin exposure Details Digoxin Buthiazide Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Calcium A serious risk of arrhythmia and cardiovascular collapse Details Digoxin Calcium Carbonate Alka-Mints Reduced digoxin exposure Details Digoxin Calcium Silicate Reduced digoxin exposure Details Digoxin Candesartan Atacand An increased digoxin exposure Details Digoxin Cannabidiol Epidiolex Increased P-gp substrate exposure Details Digoxin Carbamazepine Carbatrol Reduced digoxin exposure Details Digoxin Carvedilol Coreg Increased digoxin exposure and an increased risk of bradycardia and advanced or complete heart block Details Digoxin Celecoxib Celebrex Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Ceritinib Zykadia Increased risk of bradycardia Details Digoxin Chan Su Increased risk of digoxin toxicity Details Digoxin Chlorothiazide Diuril Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Chlorthalidone Hemiclor Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Cholestyramine Prevalite Reduced digoxin exposure Details Digoxin Choline Salicylate Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Cilnidipine An increased risk of bradycardia and an increased risk of complete heart block Details Digoxin Cimetidine Tagamet Increased digoxin exposure Details Digoxin Clarithromycin Biaxin Increased risk of digoxin toxicity Details Digoxin Clevidipine An increased risk of bradycardia and an increased risk of complete heart block Details Digoxin Clomipramine Anafranil Increased clomiPRAMINE exposure, an increased risk of clomiPRAMINE-related adverse effects, an increased digoxin exposure and an i... Details Digoxin Clonidine Duraclon An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Digoxin Clonixin Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Clopamide Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Cobicistat Tybost Increased digoxin exposure Details Digoxin Conivaptan Vaprisol Increased digoxin exposure Details Digoxin Crizotinib Xalkori An increased risk of bradycardia Details Digoxin Curcumin Altered digoxin exposure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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