Dolasetron Injection

296 interactions 421 cited references

Also sold as: Anzemet Anzemet® Injection

About Dolasetron Injection

Dolasetron injection is used to prevent and treat nausea and vomiting that may occur after surgery. Dolasetron injection should not be used to prevent or treat nausea and vomiting in people receiving cancer chemotherapy medications. Dolasetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It… Read the full Dolasetron Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Levomethadyl Mesoridazine Phenelzine Pimozide Piperaquine

16 Contraindicated 278 Major 1 Moderate 1 Minor

All (296) Contraindicated (16) Major (278) Moderate (1) Minor (1)

Contraindicated

Dolasetron Injection Apomorphine Apokyn Increased risk of profound hypotension and altered consciousness and an increased risk of QT interval prolongation, associated wit... Details Dolasetron Injection Bepridil An increased risk of QT interval prolongation Details Dolasetron Injection Cisapride Propulsid® Increased risk of QT interval prolongation Details Dolasetron Injection Dronedarone Multaq Increased risk of QT interval prolongation Details Dolasetron Injection Levoketoconazole Recorlev An increased risk of QT interval prolongation and an increased risk of torsade de pointes Details Dolasetron Injection Levomethadyl An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Mesoridazine An increased risk of QT interval prolongation Details Dolasetron Injection Phenelzine Nardil An increased risk of serotonin syndrome Details Dolasetron Injection Pimozide An increased risk of QT interval prolongation Details Dolasetron Injection Piperaquine An increased risk of QT interval prolongation Details Dolasetron Injection Saquinavir An increased risk of QT interval prolongation Details Dolasetron Injection Sparfloxacin An increased risk of QT interval prolongation Details Dolasetron Injection Terfenadine An increased risk of QT interval prolongation Details Dolasetron Injection Thioridazine An increased risk of QT interval prolongation Details Dolasetron Injection Tranylcypromine Parnate An increased risk of serotonin syndrome Details Dolasetron Injection Ziprasidone Geodon Increased risk of QT interval prolongation and an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, men... Details

Major

Dolasetron Injection Acecainide Cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Injection Adagrasib Krazati An increased risk of QT interval prolongation, torsade de pointes, polymorphic ventricular tachycardia, other serious arrhythmias Details Dolasetron Injection Ajmaline Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Alfentanil Increased risk of serotonin syndrome Details Dolasetron Injection Alfuzosin UroXatral An increased risk of QT interval prolongation Details Dolasetron Injection Almotriptan Increased risk of serotonin syndrome Details Dolasetron Injection Amineptine Increased risk of serotonin syndrome Details Dolasetron Injection Amiodarone Nexterone An increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Injection Amisulpride Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Dolasetron Injection Amitriptyline Elavil Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Amitriptylinoxide Increased risk of serotonin syndrome Details Dolasetron Injection Amoxapine Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Amphetamine Dexedrine An increased risk of serotonin syndrome Details Dolasetron Injection Anagrelide Agrylin Increased risk of QT interval prolongation Details Dolasetron Injection Aprindine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Aripiprazole Abilify An increased risk of QT interval prolongation Details Dolasetron Injection Aripiprazole Lauroxil Aristada An increased risk of QT interval prolongation Details Dolasetron Injection Arsenic Trioxide Trisenox Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Artemether An increased risk of QT interval prolongation Details Dolasetron Injection Asenapine Saphris Increased risk of QT interval prolongation Details Dolasetron Injection Astemizole Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Atazanavir Reyataz An increased risk of QT interval prolongation Details Dolasetron Injection Azimilide Cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Injection Azithromycin AzaSite An increased risk of QT interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.