Dronedarone

Major

Dronedarone Lurbinectedin Injection Zepzelca Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Dronedarone Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Dronedarone Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Dronedarone Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Dronedarone Methylergonovine Methergine Increased methylergonovine exposure and an increased risk of vasospasm, cerebral ischemia and/or ischemia of extremities Details Dronedarone Midazolam Nasal Spray Nayzilam Increased midazolam exposure and increased risk for prolonged sedation Details Dronedarone Midazolam Injection Nayzilam Increased midazolam exposure and increased risk for prolonged sedation Details Dronedarone Mitapivat Aqvesme Increased mitapivat exposure and reduced CYP3A4 substrate exposure Details Dronedarone Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Dronedarone Nadolol Corgard Increased exposure to some beta blockers and increased incidence of bradycardia Details Dronedarone Nafcillin Injection Unipen® Injection Reduced dronedarone exposure Details Dronedarone Naloxegol Movantik Increased naloxegol exposure Details Dronedarone Nebivolol Bystolic Increased exposure to some beta blockers and increased incidence of bradycardia Details Dronedarone Neratinib Nerlynx Increased neratinib exposure and risk of toxicity Details Dronedarone Nevirapine Viramune Reduced dronedarone exposure Details Dronedarone Nifedipine Adalat® Increased NIFEdipine exposure Details Dronedarone Olaparib Lynparza Increased olaparib exposure Details Dronedarone Olutasidenib Rezlidhia Reduced sensitive CYP3A substrate exposure Details Dronedarone Penbutolol Levatol® Increased exposure to some beta blockers and increased incidence of bradycardia Details

Moderate

Dronedarone Trospium / Xanomeline Cobenfy Explained Increased oral sensitive CYP3A4 substrate exposure and an increased risk on severity and frequency of sensitive CYP3A4 substrate-r... Details Dronedarone Abemaciclib Verzenio Explained Increased abemaciclib plasma concentration Details Dronedarone Avanafil Stendra Increased avanafil exposure Details Dronedarone Furosemide Injection Disal Risk of hypokalemia and hypomagnesemia Details Dronedarone Guanfacine Intuniv Increased guanfacine exposure Details Dronedarone Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Dronedarone Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details