Esomeprazole

Major

Esomeprazole Methadone Diskets Increased methadone exposure and an increased risk of opioid adverse effects Details Esomeprazole Methamphetamine Desoxyn Increased exposure to amphetamine Details Esomeprazole Methotrexate Jylamvo Increased and prolonged plasma concentration of methotrexate and its metabolite Details Esomeprazole Methylergonovine Methergine Increased methylergonovine exposure Details Esomeprazole Methylphenidate Adhansia XR® Altered pharmacodynamic and changes in release profile of methylphenidate Details Esomeprazole Mifepristone Korlym Increased miFEPRIStone exposure Details Esomeprazole Mycophenolate Mofetil Reduced mycophenolic acid exposure Details Esomeprazole Nelfinavir Viracept Decreased nelfinavir plasma concentrations and risk of diminished therapeutic effect of nelfinavir Details Esomeprazole Neratinib Nerlynx Decreased neratinib solubility, absorption, and exposure Details Esomeprazole Nifedipine Adalat® Increased NIFEdipine exposure Details Esomeprazole Nilotinib Reduced nilotinib exposure and reduced efficacy of nilotinib Details Esomeprazole Nirogacestat Ogsiveo Reduced nirogacestat exposure and reduced efficacy of nirogacestat Details Esomeprazole Nivolumab Opdivo Reduced efficacy of nivolumab Details Esomeprazole Octreotide Bynfezia Decreased octreotide bioavailability Details Esomeprazole Palbociclib Ibrance Reduced efficacy of palbociclib Details Esomeprazole Paltusotine Palsonify Reduced paltusotine exposure and reduced efficacy of paltusotine Details Esomeprazole Pazopanib Votrient Reduction in pazopanib bioavailability Details Esomeprazole Pexidartinib Turalio Reduced pexidartinib exposure Details Esomeprazole Phenobarbital Fidoquel Reduced esomeprazole exposure, reduced efficacy of esomeprazole, increased PHENobarbital exposure and an increased risk of PHENoba... Details Esomeprazole Pimozide Increased pimozide exposure Details Esomeprazole Posaconazole Noxafil Reduced posaconazole exposure and reduced efficacy of posaconazole Details Esomeprazole Primidone Mysoline Reduced esomeprazole exposure, reduced efficacy of esomeprazole, increased PHENobarbital exposure and an increased risk of PHENoba... Details Esomeprazole Rilzabrutinib Wayrilz Reduced rilzabrutinib exposure and reduced efficacy of rilzabrutinib Details Esomeprazole Roflumilast Daliresp Increased roflumilast exposure and an increased risk of roflumilast-related adverse events Details Esomeprazole Saquinavir Significant increases in saquinavir exposure Details Esomeprazole Secretin Human Chirhostim False positive secretin stimulation test results Details Esomeprazole Selpercatinib Retevmo Reduced selpercatinib exposure and reduced anti-tumor activity Details Esomeprazole Sotorasib Lumakras Reduced sotorasib exposure and anti-tumor activity Details Esomeprazole Sparsentan Filspari Reduced sparsentan exposure, reduced efficacy of sparsentan, reduced CYP2C19 substrate exposure and reduced efficacy of CYP2C19 su... Details Esomeprazole Sunitinib Sutent Reduction in sunitinib bioavailability Details Esomeprazole Tacrolimus Astagraf Increased tacrolimus exposure Details Esomeprazole Taletrectinib Ibtrozi Reduced taletrectinib exposure and reduced efficacy of taletrectinib Details Esomeprazole Thiopental Increased volume of distribution and prolonged half life of thiopental Details Esomeprazole Tramadol ConZip Increased traMADol exposure and an increased risk of seizures, serotonin syndrome and opioid toxicity Details Esomeprazole Velpatasvir Decreased velpatasvir exposure Details Esomeprazole Vismodegib Erivedge Reduced vismodegib systemic exposure Details Esomeprazole Voriconazole Vfend Increased esomeprazole exposure, an increased voriconazole exposure and an increased risk of voriconazole-related adverse effects Details Esomeprazole Ziftomenib Komzifti Reduced ziftomenib exposure and reduced efficacy of ziftomenib Details Esomeprazole Ketoconazole Topical Extina® Foam Reduced ketoconazole exposure and reduced efficacy of ketoconazole Details Esomeprazole Methotrexate Injection Abitrexate® Increased and prolonged plasma concentration of methotrexate and its metabolite Details