Ethopropazine

26 interactions 2 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Ethopropazine Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Ethopropazine Buprenorphine Belbuca Explained An increased risk of respiratory depression and CNS depression Details Ethopropazine Cabergoline Dostinex® Reduced efficacy of cabergoline and reduced efficacy of dopamine-2 receptors Details Ethopropazine Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Ethopropazine Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Ethopropazine Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Ethopropazine Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Ethopropazine Diazepam Nasal Spray Valtoco Increased risk of CNS depression Details Ethopropazine Diazepam Rectal Diastat Increased risk of CNS depression Details Ethopropazine Esketamine Nasal Spray Spravato Increased risk of sedation Details Ethopropazine Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Ethopropazine Gatifloxacin Ophthalmic Zymar® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Ethopropazine Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Ethopropazine Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Ethopropazine Hydroxychloroquine Plaquenil An increased risk of seizures Details Ethopropazine Isradipine DynaCirc® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Ethopropazine Lacosamide Injection Motpoly An increased risk of CNS depression Details Ethopropazine Levodopa Oral Inhalation Inbrija Reduce efficacy of levodopa (foslevodopa), an increased risk of exacerbating psychosis [or symptoms of Parkinson's disease: delusi... Details Ethopropazine Lithium Carbonate Lithobid Weakness, dyskinesias, increased extrapyramidal symptoms, encephalopathy, and brain damage Details Ethopropazine Metoclopramide Injection Gimoti Increased risk of CNS depression Details Ethopropazine Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Ethopropazine Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Ethopropazine Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details Ethopropazine Octreotide Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Ethopropazine Octreotide Injection Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.