Flurbiprofen

299 interactions 378 cited references
Also sold as: Ansaid Ansaid® Lurbipr Lurbiro Ocufen
About Flurbiprofen

Flurbiprofen is an NSAID used to relieve pain, swelling, and stiffness from osteoarthritis and rheumatoid arthritis. Read the full Flurbiprofen drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Injection Ketorolac Ketorolac Ophthalmic Ketorolac Nasal Spray Escitalopram Pemetrexed Injection
4 Contraindicated 235 Major 60 Moderate
All (299) Contraindicated (4) Major (235) Moderate (60)

Moderate

Flurbiprofen Lisinopril Prinivil Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Atenolol Tenormin Reduced antihypertensive effect Details Flurbiprofen Acebutolol Sectral® Reduced antihypertensive effect Details Flurbiprofen Benazepril Lotensin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Azilsartan Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Betaxolol Betoptic S Reduced antihypertensive effect Details Flurbiprofen Betaxolol Ophthalmic Betoptic® Reduced antihypertensive effect Details Flurbiprofen Bisoprolol Zebeta® Reduced antihypertensive effect Details Flurbiprofen Captopril Capoten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Desmopressin Nasal Concentraid® Increased risk of water intoxication with hyponatremia Details Flurbiprofen Enalapril Epaned Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Eprosartan Teveten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Esmolol Brevibloc Reduced antihypertensive effect Details Flurbiprofen Anisindione An increased risk of bleeding Details Flurbiprofen Azilsartan Medoxomil Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Candesartan Atacand Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Carteolol Reduced antihypertensive effect Details Flurbiprofen Carvedilol Coreg Reduced antihypertensive effect Details Flurbiprofen Celiprolol Reduced antihypertensive effect Details Flurbiprofen Ciprofloxacin An increased risk of convulsions Details Flurbiprofen Desmopressin DDAVP Increased risk of water intoxication with hyponatremia Details Flurbiprofen Dicumarol An increased risk of bleeding Details Flurbiprofen Enalaprilat Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Fosinopril Monopril® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Ginkgo An increased risk of bleeding Details Flurbiprofen Irbesartan Avapro Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Labetalol Normodyne® Reduced antihypertensive effect Details Flurbiprofen Levobunolol Betagan Reduced antihypertensive effect Details Flurbiprofen Levofloxacin Levaquin An increased risk of seizures Details Flurbiprofen L-Methylfolate Decreased l-methylfolate efficacy Details Flurbiprofen Losartan Arbli Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Ma Huang Increased risk of developing gastric mucosal lesions Details Flurbiprofen Mavacamten Camzyos Reduced CYP2C9 substrate exposure and reduced efficacy of CYP2C9 substrate Details Flurbiprofen Metipranolol Reduced antihypertensive effect Details Flurbiprofen Metoprolol Kapspargo Reduced antihypertensive effect Details Flurbiprofen Mifepristone Korlym Increased NSAID exposure Details Flurbiprofen Moexipril Univasc® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Nadolol Corgard Reduced antihypertensive effect Details Flurbiprofen Nebivolol Bystolic Reduced antihypertensive effect Details Flurbiprofen Norfloxacin An increased risk of seizures Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.