Gatifloxacin Ophthalmic

283 interactions 389 cited references
Also sold as: Zymar® Zymaxid Zymaxid®
About Gatifloxacin Ophthalmic

Gatifloxacin ophthalmic solution is used to treat bacterial conjunctivitis (pinkeye; infection of the membrane that covers the outside of the eyeballs and the inside of the eyelids) in adults and children 1 year of age and older. Gatifloxacin is in a class of antibiotics called fluoroquinolones. It works by killing the… Read the full Gatifloxacin Ophthalmic drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Dronedarone Levoketoconazole Mesoridazine Pimozide Piperaquine Saquinavir
12 Contraindicated 254 Major 17 Moderate
All (283) Contraindicated (12) Major (254) Moderate (17)

Major

Gatifloxacin Ophthalmic Imipramine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Gatifloxacin Ophthalmic Inotuzumab Ozogamicin Besponsa Increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Insulin Afrezza Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Insulin Aspart, Recombinant Fiasp Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Insulin Bovine Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Insulin Degludec Tresiba Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Insulin Detemir Levemir Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Insulin Glulisine Apidra Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Insulin Lispro, Recombinant Admelog Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Isoflurane Fluriso An increased risk of QT interval prolongation and torsade de pointes Details Gatifloxacin Ophthalmic Itraconazole Sporanox An increased risk of QT interval prolongation and torsade de pointes Details Gatifloxacin Ophthalmic Ivabradine Corlanor Increased risk of QT prolongation Details Gatifloxacin Ophthalmic Ivosidenib Tibsovo An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Ketoconazole Extina An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Lapatinib Tykerb An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Lefamulin Xenleta Increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Gatifloxacin Ophthalmic Leuprolide Eligard Increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Levofloxacin Levaquin Increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Linagliptin Tradjenta Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Liraglutide Saxenda Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Lixisenatide Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Gatifloxacin Ophthalmic Lofepramine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Gatifloxacin Ophthalmic Lofexidine Increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Lonafarnib Zokinvy An increased risk of QT interval prolongation and torsade de pointes Details Gatifloxacin Ophthalmic Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Gatifloxacin Ophthalmic Lopinavir An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Lumefantrine An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Macimorelin Increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Magnesium Sulfate May reduce absorption of fluoroquinolone antibiotics Details Gatifloxacin Ophthalmic Mavorixafor Xolremdi An increased risk of QT interval prolongation and torsade de pointes Details Gatifloxacin Ophthalmic Mefloquine Lariam® An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Metformin Fortamet® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Methadone Diskets Increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Gatifloxacin Ophthalmic Methotrimeprazine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Gatifloxacin Ophthalmic Methylprednisolone Depo-Medrol An increased risk of tendon rupture Details Gatifloxacin Ophthalmic Metronidazole Flagyl An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Mifepristone Korlym An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Miglitol Glyset® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.