Gatifloxacin Ophthalmic

283 interactions 389 cited references
Also sold as: Zymar® Zymaxid Zymaxid®
About Gatifloxacin Ophthalmic

Gatifloxacin ophthalmic solution is used to treat bacterial conjunctivitis (pinkeye; infection of the membrane that covers the outside of the eyeballs and the inside of the eyelids) in adults and children 1 year of age and older. Gatifloxacin is in a class of antibiotics called fluoroquinolones. It works by killing the… Read the full Gatifloxacin Ophthalmic drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Dronedarone Levoketoconazole Mesoridazine Pimozide Piperaquine Saquinavir
12 Contraindicated 254 Major 17 Moderate
All (283) Contraindicated (12) Major (254) Moderate (17)

Moderate

Gatifloxacin Ophthalmic Aluminum Carbonate, Basic Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Aluminum Hydroxide AlternaGEL® Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Aluminum Phosphate Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Aminolevulinic Acid Increased risk of phototoxic skin reaction (ie, severe sunburn) Details Gatifloxacin Ophthalmic Dandelion Decreased fluoroquinolone effectiveness Details Gatifloxacin Ophthalmic Didanosine Videx® Decreased gatifloxacin effectiveness Details Gatifloxacin Ophthalmic Digoxin Cardoxin® An increased risk of digoxin toxicity (nausea, vomiting, arrhythmias) Details Gatifloxacin Ophthalmic Dihydroxyaluminum Aminoacetate Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Dihydroxyaluminum Sodium Carbonate Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Iron Decreased gatifloxacin effectiveness Details Gatifloxacin Ophthalmic Lanthanum Carbonate Fosrenol Reduced bioavailability of quinolone antibiotics Details Gatifloxacin Ophthalmic Magaldrate Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Magnesium Decreased gatifloxacin effectiveness Details Gatifloxacin Ophthalmic Probenecid An increase in the serum level of gatifloxacin Details Gatifloxacin Ophthalmic Quercetin Reduced fluoroquinolone effectiveness Details Gatifloxacin Ophthalmic Strontium Ranelate Decreased bioavailability and exposure of strontium ranelate Details Gatifloxacin Ophthalmic Zinc Decreased gatifloxacin effectiveness Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.