Gatifloxacin Ophthalmic

283 interactions 389 cited references

Also sold as: Zymar® Zymaxid Zymaxid®

About Gatifloxacin Ophthalmic

Gatifloxacin ophthalmic solution is used to treat bacterial conjunctivitis (pinkeye; infection of the membrane that covers the outside of the eyeballs and the inside of the eyelids) in adults and children 1 year of age and older. Gatifloxacin is in a class of antibiotics called fluoroquinolones. It works by killing the… Read the full Gatifloxacin Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Dronedarone Levoketoconazole Mesoridazine Pimozide Piperaquine Saquinavir

12 Contraindicated 254 Major 17 Moderate

All (283) Contraindicated (12) Major (254) Moderate (17)

Major

Gatifloxacin Ophthalmic Thiethylperazine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Gatifloxacin Ophthalmic Tolazamide Tolinase® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Tolbutamide Orinase® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Toremifene Fareston An increased risk of QT interval prolongation, ventricular tachycardia or an increased risk of torsade de pointes Details Gatifloxacin Ophthalmic Tramadol ConZip An increased risk of seizure Details Gatifloxacin Ophthalmic Trazodone Raldesy An increased risk of QT interval prolongation and an increased risk of cardiac arrythmia Details Gatifloxacin Ophthalmic Triamcinolone Aller-Cort An increased risk of tendon rupture Details Gatifloxacin Ophthalmic Triclabendazole Egaten An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Trifluoperazine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Gatifloxacin Ophthalmic Triflupromazine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Gatifloxacin Ophthalmic Trimeprazine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Gatifloxacin Ophthalmic Trimipramine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Gatifloxacin Ophthalmic Triptorelin Increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Vandetanib Caprelsa An increased risk of QT interval prolongation and Torsades de pointes Details Gatifloxacin Ophthalmic Vardenafil Levitra An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Vemurafenib Zelboraf Increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Venlafaxine An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Vepdegestrant Veppanu An increased risk of QT interval prolongation and an increased risk of torsade de pointes, polymorphic ventricular tachycardia, ot... Details Gatifloxacin Ophthalmic Vilanterol An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Vinflunine Increased risk of QT-interval prolongation Details Gatifloxacin Ophthalmic Voclosporin Lupkynis An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Voglibose Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Gatifloxacin Ophthalmic Voriconazole Vfend An increased risk of QT interval prolongation Details Gatifloxacin Ophthalmic Warfarin Coumadin An increased risk of bleeding Details Gatifloxacin Ophthalmic Ziftomenib Komzifti An increased risk of QT interval prolongation and torsade de pointes Details Gatifloxacin Ophthalmic Zuclopenthixol An increased risk of QT interval prolongation Details

Moderate

Gatifloxacin Ophthalmic Aluminum Carbonate, Basic Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Aluminum Hydroxide AlternaGEL® Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Aluminum Phosphate Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Aminolevulinic Acid Increased risk of phototoxic skin reaction (ie, severe sunburn) Details Gatifloxacin Ophthalmic Dandelion Decreased fluoroquinolone effectiveness Details Gatifloxacin Ophthalmic Didanosine Videx® Decreased gatifloxacin effectiveness Details Gatifloxacin Ophthalmic Digoxin Cardoxin® An increased risk of digoxin toxicity (nausea, vomiting, arrhythmias) Details Gatifloxacin Ophthalmic Dihydroxyaluminum Aminoacetate Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Dihydroxyaluminum Sodium Carbonate Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Iron Decreased gatifloxacin effectiveness Details Gatifloxacin Ophthalmic Lanthanum Carbonate Fosrenol Reduced bioavailability of quinolone antibiotics Details Gatifloxacin Ophthalmic Magaldrate Loss of gatifloxacin efficacy Details Gatifloxacin Ophthalmic Magnesium Decreased gatifloxacin effectiveness Details Gatifloxacin Ophthalmic Probenecid An increase in the serum level of gatifloxacin Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.