Glecaprevir
48 interactions 4 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Moderate
Glecaprevir Acarbose Prandase® Explained Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Alogliptin Nesina Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Canagliflozin Invokana Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Dapagliflozin Farxiga Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Digoxin Cardoxin® Increased digoxin exposure Details Glecaprevir Dofetilide Tikosyn Increased dofetilide exposure Details Glecaprevir Dulaglutide Injection Trulicity Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Encorafenib Braftovi Increased OATP1B1 substrate exposure, increased OATP1B3 substrate exposure, increased risk of OATP1B1 substrate-related toxicities... Details Glecaprevir Ertugliflozin Steglatro Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Exenatide Injection Bydureon Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Fluvastatin Lescol Increased fluvastatin exposure and an increased risk of myopathy Details Glecaprevir Glimepiride Amaryl Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Glipizide Glucotrol Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Glecaprevir Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Glecaprevir Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Insulin Detemir (Rdna Origin) Injection Levemir Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Insulin Glulisine (Rdna Origin) Injection Apidra Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Linagliptin Tradjenta Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Liraglutide Injection Saxenda Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Lixisenatide Injection Adlyxin® Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Metformin Fortamet® Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Miglitol Glyset® Altered glycemic control resulting in severe symptomatic hypoglycemia Details Glecaprevir Nateglinide Starlix® Altered glycemic control resulting in severe symptomatic hypoglycemia DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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