Glyburide

Name: Glyburide Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

79 interactions 4 explained in plain English

Also sold as: DiaBeta® Glynase Glynase® Micronase®

About Glyburide

Glyburide is a sulfonylurea medication that lowers blood sugar in people with type 2 diabetes. Read the full Glyburide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acarbose Moxifloxacin Ophthalmic Belumosudil Orlistat Fluorouracil Injection Disopyramide

42 Major 37 Moderate

All (79) Major (42) Moderate (37)

Major

Glyburide Ofloxacin Otic Floxin® Otic Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Glyburide Orlistat Alli An increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.