Granisetron Transdermal Patch

281 interactions 403 cited references
Also sold as: Sancuso Sancuso®
About Granisetron Transdermal Patch

Granisetron transdermal patches are used to prevent nausea and vomiting caused by chemotherapy. Granisetron is in a class of medications called 5HT3 inhibitors. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting. Read the full Granisetron Transdermal Patch drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Phenelzine Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine
16 Contraindicated 265 Major
All (281) Contraindicated (16) Major (265)

Major

Granisetron Transdermal Patch Hydroxytryptophan Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Hydroxyzine An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Ibutilide Corvert An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Iloperidone Fanapt Increased risk of QT interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Imipramine Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Transdermal Patch Inotuzumab Ozogamicin Besponsa Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Iproniazid Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Isocarboxazid Marplan Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Isoflurane Fluriso An increased risk of QT interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Itraconazole Sporanox An increased risk of QT interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Ivabradine Corlanor Increased risk of QT prolongation Details Granisetron Transdermal Patch Ivosidenib Tibsovo An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Ketobemidone Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Ketoconazole Extina Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Kratom An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lapatinib Tykerb An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Lasmiditan Reyvow Increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, mental status changes) Details Granisetron Transdermal Patch Lefamulin Xenleta Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Granisetron Transdermal Patch Leuprolide Eligard Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Levofloxacin Levaquin Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Levomilnacipran Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Levorphanol Xyvona An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Linezolid Zyvox Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lisdexamfetamine Arynta An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lithium Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lofepramine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lofexidine Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Lonafarnib Zokinvy An increased risk of QT interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Granisetron Transdermal Patch Lopinavir An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Lorcaserin Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lumefantrine An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Macimorelin Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Mavorixafor Xolremdi An increased risk of QT interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Mefloquine Lariam® An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Melitracen Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Meperidine Demerol Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Metaxalone Skelaxin Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Methadone Diskets Increased risk of serotonin syndrome and QT-interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.