Granisetron Transdermal Patch

281 interactions 403 cited references
Also sold as: Sancuso Sancuso®
About Granisetron Transdermal Patch

Granisetron transdermal patches are used to prevent nausea and vomiting caused by chemotherapy. Granisetron is in a class of medications called 5HT3 inhibitors. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting. Read the full Granisetron Transdermal Patch drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Phenelzine Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine
16 Contraindicated 265 Major
All (281) Contraindicated (16) Major (265)

Major

Granisetron Transdermal Patch Methamphetamine Desoxyn An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Methylene Blue Provayblue Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Metronidazole Flagyl An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Mifepristone Korlym An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Milnacipran Savella Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Milsaperidone An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Mirtazapine Mirataz Increased risk of serotonin syndrome, an increased risk of QT interval prolongation and an increased risk of torsades de pointes Details Granisetron Transdermal Patch Mobocertinib Exkivity An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Moclobemide Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Morphine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Morphine Sulfate Liposome Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Moxifloxacin Avelox Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Nalbuphine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Naratriptan Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Nefazodone Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Nelfinavir Viracept Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Nialamide Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Nicomorphine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Nilotinib An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Norfloxacin An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Nortriptyline Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Octreotide Bynfezia An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Ofloxacin Floxin® An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Olanzapine An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Oliceridine Olinvyk Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Olodaterol Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Granisetron Transdermal Patch Ondansetron An increased risk of serotonin syndrome and QT interval prolongation Details Granisetron Transdermal Patch Opipramol Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Opium Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Opium Alkaloids Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Osilodrostat Isturisa Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Osimertinib Tagrisso Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Oxaliplatin Increased risk of QT-interval prolongation Details Granisetron Transdermal Patch Oxycodone Oxaydo Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Oxymorphone Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Ozanimod Additive effects on heart rate Details Granisetron Transdermal Patch Pacritinib Vonjo® An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Paliperidone Erzofri An increased risk of QT interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Palonosetron Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Panobinostat Farydak Increased risk of QT interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.