Granisetron Transdermal Patch

281 interactions 403 cited references
Also sold as: Sancuso Sancuso®
About Granisetron Transdermal Patch

Granisetron transdermal patches are used to prevent nausea and vomiting caused by chemotherapy. Granisetron is in a class of medications called 5HT3 inhibitors. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting. Read the full Granisetron Transdermal Patch drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Phenelzine Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine
16 Contraindicated 265 Major
All (281) Contraindicated (16) Major (265)

Major

Granisetron Transdermal Patch Lasmiditan Reyvow Increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, mental status changes) Details Granisetron Transdermal Patch Lefamulin Xenleta Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Granisetron Transdermal Patch Leuprolide Eligard Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Levofloxacin Levaquin Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Levomilnacipran Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Levorphanol Xyvona An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Linezolid Zyvox Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lisdexamfetamine Arynta An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lithium Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lofepramine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lofexidine Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Lonafarnib Zokinvy An increased risk of QT interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Granisetron Transdermal Patch Lopinavir An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Lorcaserin Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Lumefantrine An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Macimorelin Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Mavorixafor Xolremdi An increased risk of QT interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Mefloquine Lariam® An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Melitracen Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Meperidine Demerol Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Metaxalone Skelaxin Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Methadone Diskets Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Transdermal Patch Methamphetamine Desoxyn An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Methylene Blue Provayblue Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Metronidazole Flagyl An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Mifepristone Korlym An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Milnacipran Savella Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Milsaperidone An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Mirtazapine Mirataz Increased risk of serotonin syndrome, an increased risk of QT interval prolongation and an increased risk of torsades de pointes Details Granisetron Transdermal Patch Mobocertinib Exkivity An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Moclobemide Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Morphine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Morphine Sulfate Liposome Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Moxifloxacin Avelox Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Nalbuphine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Naratriptan Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Nefazodone Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Nelfinavir Viracept Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.