Lamivudine

Name: Lamivudine Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

8 interactions 207 cited references

Also sold as: Epivir Epivir-HBV® Epivir®

About Lamivudine

Lamivudine (Epivir) is used along with other medications to treat human immunodeficiency virus (HIV) infection in adults and children 3 months of age and older. Lamivudine (Epivir-HBV) is used to treat hepatitis B infection. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRT… Read the full Lamivudine drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Islatravir Cabotegravir Atidarsagene Autotemcel Etuvetidigene Autotemcel Horsetail Orlistat

1 Contraindicated 7 Major

All (8) Contraindicated (1) Major (7)

Contraindicated

Lamivudine Islatravir Reduced islatravir-triphosphate exposure and reduced efficacy of islatravir Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.