Levonorgestrel Intrauterine System

Major

Levonorgestrel Intrauterine System Colesevelam Welchol Decreased contraceptive effectiveness Details Levonorgestrel Intrauterine System Cyclacillin Decreased contraceptive effectiveness Details Levonorgestrel Intrauterine System Cyclosporine Atopica Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Levonorgestrel Intrauterine System Dabrafenib Tafinlar Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Darunavir Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and an increased darunavir exposure Details Levonorgestrel Intrauterine System Demeclocycline Declomycin® Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Intrauterine System Dexamethasone Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Dextroamphetamine Dexedrine Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Levonorgestrel Intrauterine System Dicloxacillin Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Intrauterine System Dipyrone Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Doxycycline Acticlate Reduced efficacy of oral contraceptive Details Levonorgestrel Intrauterine System Efavirenz Decreased levonorgestrel exposure and increased risk of contraceptive failure Details Levonorgestrel Intrauterine System Elafibranor Iqirvo Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and/or an increased risk of breakthrough ble... Details Levonorgestrel Intrauterine System Elagolix Orilissa Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Elvitegravir Altered contraceptive effectiveness and risk of side effects Details Levonorgestrel Intrauterine System Enasidenib Idhifa Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Encorafenib Braftovi Reduced hormonal contraceptives exposure and reduced efficacy of hormonal contraceptives Details Levonorgestrel Intrauterine System Enzalutamide Xtandi Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Eravacycline Xerava Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Intrauterine System Erythromycin Erythrocin Stearate Increased CYP3A4 substrate exposure and an increased risk of CYP3A4-substrate-related adverse effects Details Levonorgestrel Intrauterine System Eslicarbazepine Acetate Aptiom Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Etravirine Intelence Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Exenatide Bydureon Reduced oral contraceptives absorption and reduced efficacy of oral contraceptives Details Levonorgestrel Intrauterine System Felbamate Felbatol Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding or contraceptiv... Details Levonorgestrel Intrauterine System Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Levonorgestrel Intrauterine System Fluconazole Diflucan Increased levonorgestrel exposure Details Levonorgestrel Intrauterine System Fosamprenavir Lexiva Reduced amprenavir exposure, altered hormonal levels, loss of contraceptive efficacy, and an increased risk of liver enzyme elevat... Details Levonorgestrel Intrauterine System Fosaprepitant Emend Injection Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and an increased risk of breakthrough bleedin... Details Levonorgestrel Intrauterine System Fosphenytoin Cerebyx Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Griseofulvin Fulvicin P/G Decreased contraceptive effectiveness Details Levonorgestrel Intrauterine System Guar Gum Reduced contraceptive effectiveness Details Levonorgestrel Intrauterine System Hydrocortisone Ala-Cort Altered (reduced/increased) hydrocortisone exposure, reduced efficacy of hydrocortisone and an increased risk of hydrocortisone-re... Details Levonorgestrel Intrauterine System Indinavir Increased levonorgestrel exposure Details Levonorgestrel Intrauterine System Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Levonorgestrel Intrauterine System Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Levonorgestrel Intrauterine System Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Levonorgestrel Intrauterine System Isotretinoin Absorica Decreased effectiveness of hormonal contraceptives Details Levonorgestrel Intrauterine System Itraconazole Sporanox Increased levonorgestrel exposure Details Levonorgestrel Intrauterine System Ivosidenib Tibsovo Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Ketoconazole Extina Increased levonorgestrel exposure Details