Levonorgestrel Intrauterine System

Major

Levonorgestrel Intrauterine System Phenylbutazone Equi-Phar Reduced contraceptive exposure, reduced efficacy of hormonal contraceptives and an increased risk of breakthrough bleeding and/or... Details Levonorgestrel Intrauterine System Phenytoin Dilantin Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Pimozide Increased pimozide exposure and an increased risk of pimozide-related adverse reactions Details Levonorgestrel Intrauterine System Piperacillin Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Intrauterine System Pitolisant Wakix Reduced efficacy of hormonal contraceptives Details Levonorgestrel Intrauterine System Pivampicillin Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Intrauterine System Prednisolone Flo-Pred® Increased prednisoLONE exposure and an increased risk of corticosteroid side effects (neuropsychiatric reactions, fluid and electr... Details Levonorgestrel Intrauterine System Prednisone Deltasone Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Primidone Mysoline Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Red Clover Altered contraceptive effectiveness or increased side effects Details Levonorgestrel Intrauterine System Repotrectinib Augtyro Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Rifabutin Mycobutin Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Rifampin Rifadin Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Rifapentine Priftin Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Roflumilast Daliresp Increased roflumilast exposure and an increased risk of roflumilast-related adverse events Details Levonorgestrel Intrauterine System Rolitetracycline Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Intrauterine System Rufinamide Banzel Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Saquinavir Altered (increased and reduced) levonorgestrel exposure Details Levonorgestrel Intrauterine System Sarecycline Seysara Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Intrauterine System Secobarbital Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptive and an increased risk of breakthrough bleeding... Details Levonorgestrel Intrauterine System Sotagliflozin Inpefa Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Sotorasib Lumakras Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System St John's Wort Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Intrauterine System Sugammadex Decreased contraceptive serum concentration and efficacy Details Levonorgestrel Intrauterine System Sultamicillin Decreased contraceptive effectiveness Details Levonorgestrel Intrauterine System Sunvozertinib Zegfrovy Reduced hormonal contraceptives exposure and reduced efficacy of hormonal contraceptives Details Levonorgestrel Intrauterine System Tazemetostat Tazverik Reduced hormonal contraceptives exposure and reduced efficacy of hormonal contraceptives Details Levonorgestrel Intrauterine System Telaprevir Decreased contraceptive effectiveness Details Levonorgestrel Intrauterine System Telotristat Ethyl Xermelo Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Temocillin Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Intrauterine System Tetracycline Achromycin V® Decreased contraceptive effectiveness Details Levonorgestrel Intrauterine System Theophylline Accurbron® Increased theophylline exposure and theophylline toxicity (nausea, vomiting, palpitations, seizures) Details Levonorgestrel Intrauterine System Thiopental Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding or contraceptiv... Details Levonorgestrel Intrauterine System Thioridazine Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Intrauterine System Ticarcillin Decreased contraceptive effectiveness Details Levonorgestrel Intrauterine System Tigecycline Tygacil Decreased contraceptive effectiveness Details Levonorgestrel Intrauterine System Tipranavir Aptivus Altered (increased and reduced) levonorgestrel exposure Details Levonorgestrel Intrauterine System Tirzepatide Mounjaro Reduced absorption of oral contraceptives Details Levonorgestrel Intrauterine System Tizanidine Increased tiZANidine exposure and an increased risk of tiZANidine-related hypotension, bradycardia or increased drowsiness Details Levonorgestrel Intrauterine System Tocilizumab Actemra Reduced oral contraceptives exposure and reduced efficacy of oral contraceptives Details