Lixisenatide Injection

174 interactions 162 cited references
Also sold as: Adlyxin® Soliqua® (as a combination product containing Insulin Glargine and Lixisenatide)
About Lixisenatide Injection

Lixisenatide injection is used along with diet and exercise to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Lixisenatide injection is not used to treat type 1 diabetes (condition in which the body does not produce insuli… Read the full Lixisenatide Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Trovafloxacin Estradiol Enoxacin Drospirenone Dienogest Desogestrel
54 Major 120 Moderate
All (174) Major (54) Moderate (120)

Major

Lixisenatide Injection Norfloxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Norgestimate Decreased absorption of oral contraceptives Details Lixisenatide Injection Norgestrel Decreased absorption of oral contraceptives Details Lixisenatide Injection Octreotide Acetate An increased risk of hypoglycemia and impaired glucose regulation Details Lixisenatide Injection Ofloxacin Floxin® Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Pasireotide Diaspartate An increased risk of hypoglycemia and impaired glucose regulation Details Lixisenatide Injection Polythiazide An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Somatrogon-Ghla Reduced insulin sensitivity Details Lixisenatide Injection Sparfloxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Thioctic Acid Increased risk of hypoglycemia Details Lixisenatide Injection Tolazamide Tolinase® Increased risk of hypoglycemia Details Lixisenatide Injection Tolbutamide Orinase® Increased risk of hypoglycemia Details Lixisenatide Injection Triamterene Dyrenium An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Trovafloxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details

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