Lixisenatide Injection

174 interactions 162 cited references

Also sold as: Adlyxin® Soliqua® (as a combination product containing Insulin Glargine and Lixisenatide)

About Lixisenatide Injection

Lixisenatide injection is used along with diet and exercise to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Lixisenatide injection is not used to treat type 1 diabetes (condition in which the body does not produce insuli… Read the full Lixisenatide Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Trovafloxacin Estradiol Enoxacin Drospirenone Dienogest Desogestrel

54 Major 120 Moderate

All (174) Major (54) Moderate (120)

Moderate

Lixisenatide Injection Enalapril Epaned An increased risk of hypoglycemia Details Lixisenatide Injection Enalaprilat An increased risk of hypoglycemia Details Lixisenatide Injection Erythromycin Erythrocin Stearate Delayed therapeutic effect Details Lixisenatide Injection Esmolol Brevibloc Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Flumequine Delayed therapeutic effect Details Lixisenatide Injection Fosfomycin Contepo Delayed therapeutic effect Details Lixisenatide Injection Fosinopril Monopril® An increased risk of hypoglycemia Details Lixisenatide Injection Framycetin Delayed therapeutic effect Details Lixisenatide Injection Fusidic Acid Delayed therapeutic effect Details Lixisenatide Injection Glecaprevir Altered glycemic control resulting in severe symptomatic hypoglycemia Details Lixisenatide Injection Insulin Afrezza An increased risk of hypoglycemia Details Lixisenatide Injection Insulin Aspart, Recombinant Fiasp An increased risk of hypoglycemia Details Lixisenatide Injection Insulin Bovine An increased risk of hypoglycemia Details Lixisenatide Injection Insulin Degludec Tresiba An increased risk of hypoglycemia Details Lixisenatide Injection Insulin Detemir Levemir An increased risk of hypoglycemia Details Lixisenatide Injection Insulin Glargine, Recombinant Basaglar An increased risk of hypoglycemia Details Lixisenatide Injection Insulin Glulisine Apidra An increased risk of hypoglycemia Details Lixisenatide Injection Insulin Lispro, Recombinant Admelog An increased risk of hypoglycemia Details Lixisenatide Injection Josamycin Delayed therapeutic effect Details Lixisenatide Injection Kanamycin Delayed therapeutic effect Details Lixisenatide Injection Labetalol Normodyne® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Levobunolol Betagan Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Levothyroxine Ermeza Worsening of glycemic control Details Lixisenatide Injection Linezolid Zyvox Delayed therapeutic effect Details Lixisenatide Injection Lisinopril Prinivil An increased risk of hypoglycemia Details Lixisenatide Injection Lymecycline Delayed therapeutic effect Details Lixisenatide Injection Mepartricin Delayed therapeutic effect Details Lixisenatide Injection Methacycline Delayed therapeutic effect Details Lixisenatide Injection Metipranolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Metoprolol Kapspargo Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Metronidazole Flagyl Delayed therapeutic effect Details Lixisenatide Injection Minocycline Amzeeq Delayed therapeutic effect Details Lixisenatide Injection Miokamycin Delayed therapeutic effect Details Lixisenatide Injection Moexipril Univasc® An increased risk of hypoglycemia Details Lixisenatide Injection Nadolol Corgard Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Nafcillin Delayed therapeutic effect Details Lixisenatide Injection Nalidixic Acid Delayed therapeutic effect Details Lixisenatide Injection Nebivolol Bystolic Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Nimorazole Delayed therapeutic effect Details Lixisenatide Injection Nitrofurantoin Furadantin Delayed therapeutic effect Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.