Lixisenatide Injection

174 interactions 162 cited references

Also sold as: Adlyxin® Soliqua® (as a combination product containing Insulin Glargine and Lixisenatide)

About Lixisenatide Injection

Lixisenatide injection is used along with diet and exercise to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Lixisenatide injection is not used to treat type 1 diabetes (condition in which the body does not produce insuli… Read the full Lixisenatide Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Trovafloxacin Estradiol Enoxacin Drospirenone Dienogest Desogestrel

54 Major 120 Moderate

All (174) Major (54) Moderate (120)

Moderate

Lixisenatide Injection Oleandomycin Delayed therapeutic effect Details Lixisenatide Injection Ornidazole Delayed therapeutic effect Details Lixisenatide Injection Oxprenolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Oxytetracycline Delayed therapeutic effect Details Lixisenatide Injection Paromomycin Delayed therapeutic effect Details Lixisenatide Injection Pazufloxacin Delayed therapeutic effect Details Lixisenatide Injection Pefloxacin Delayed therapeutic effect Details Lixisenatide Injection Penbutolol Levatol® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Penicillin G Delayed therapeutic effect Details Lixisenatide Injection Penicillin V Delayed therapeutic effect Details Lixisenatide Injection Perindopril Aceon An increased risk of hypoglycemia Details Lixisenatide Injection Pibrentasvir Altered glycemic control resulting in severe symptomatic hypoglycemia Details Lixisenatide Injection Pindolol Visken® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Pipemidic Acid Delayed therapeutic effect Details Lixisenatide Injection Practolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Proguanil Delayed therapeutic effect Details Lixisenatide Injection Propranolol Hemangeol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Pyrimethamine Delayed therapeutic effect Details Lixisenatide Injection Quinapril Accupril An increased risk of hypoglycemia Details Lixisenatide Injection Ramipril Altace An increased risk of hypoglycemia Details Lixisenatide Injection Rifabutin Mycobutin Delayed therapeutic effect Details Lixisenatide Injection Rifampin Rifadin Delayed therapeutic effect Details Lixisenatide Injection Rifapentine Priftin Delayed therapeutic effect Details Lixisenatide Injection Rifaximin XIFAXAN Delayed therapeutic effect Details Lixisenatide Injection Rokitamycin Delayed therapeutic effect Details Lixisenatide Injection Rosoxacin Delayed therapeutic effect Details Lixisenatide Injection Rufloxacin Delayed therapeutic effect Details Lixisenatide Injection Secnidazole Solosec Delayed therapeutic effect Details Lixisenatide Injection Semaglutide Ozempic Increased risk of semaglutide-related adverse effects Details Lixisenatide Injection Sotalol Betapace Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Spiramycin Delayed therapeutic effect Details Lixisenatide Injection Sulfamethoxazole Sustain Delayed therapeutic effect Details Lixisenatide Injection Sultamicillin Delayed therapeutic effect Details Lixisenatide Injection Tedizolid Phosphate Sivextro Delayed therapeutic effect Details Lixisenatide Injection Teicoplanin Delayed therapeutic effect Details Lixisenatide Injection Tetracycline Achromycin V® Delayed therapeutic effect Details Lixisenatide Injection Timolol Betimol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Trandolapril Mavik® An increased risk of hypoglycemia Details Lixisenatide Injection Tranylcypromine Parnate An increased risk of hypoglycemia Details Lixisenatide Injection Trimethoprim Primsol Delayed therapeutic effect Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.