Loteprednol Ophthalmic

Name: Loteprednol Ophthalmic Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

29 interactions 90 cited references

Also sold as: Alrex Alrex® Eysuvis Eysuvis® Inveltys Inveltys® Lotemax Lotemax® Lotemax® SM Zylet® (as a combination product containing Loteprednol, Tobramycin)

About Loteprednol Ophthalmic

Ophthalmic loteprednol products are used to treat different eye conditions: Loteprednol (Inveltys, Lotemax, Lotemax SM) is used to treat swelling and pain after cataract surgery (procedure to treat clouding of the lens in the eye). Loteprednol (Alrex) is used to reduce eye redness, itching, and swelling caused by seaso… Read the full Loteprednol Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Desmopressin Mifepristone Aspirin Bemiparin Carbamazepine Cosyntropin

2 Contraindicated 18 Major 9 Moderate

All (29) Contraindicated (2) Major (18) Moderate (9)

Contraindicated

Loteprednol Ophthalmic Desmopressin DDAVP Increased risk of severe hyponatremia Details Loteprednol Ophthalmic Mifepristone Korlym An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.