Loxoprofen

91 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Loxoprofen Amitriptyline Elavil Explained An increased risk of bleeding Details Loxoprofen Sertraline Explained An increased risk of bleeding Details Loxoprofen Apixaban Eliquis Explained An increased risk of bleeding Details Loxoprofen Aspirin Acuprin® An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Loxoprofen Aspirin Rectal Aspirin An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Loxoprofen Betrixaban Bevyxxa® An increased risk of bleeding Details Loxoprofen Anagrelide Agrylin An increased risk of bleeding Details Loxoprofen Bromfenac Ophthalmic Bromday® Increased risk of bleeding Details Loxoprofen Budesonide Entocort Increased risk of gastrointestinal ulcer or bleeding Details Loxoprofen Budesonide Nasal Spray Rhinocort Increased risk of gastrointestinal ulcer or bleeding Details Loxoprofen Budesonide Oral Inhalation Pulmicort Increased risk of gastrointestinal ulcer or bleeding Details Loxoprofen Clopidogrel Plavix An increased risk of bleeding Details Loxoprofen Cyclosporine Injection Atopica An increased risk of cycloSPORINE nephrotoxicity Details Loxoprofen Cyclosporine Ophthalmic Cequa An increased risk of cycloSPORINE nephrotoxicity Details Loxoprofen Dabigatran Pradaxa® An increased risk of bleeding Details Loxoprofen Dabigatran Etexilate An increased risk of bleeding Details Loxoprofen Dalteparin Injection Fragmin An increased risk of bleeding Details Loxoprofen Deflazacort Emflaza Increased risk of gastrointestinal ulcer or bleeding Details Loxoprofen Dexamethasone Injection Decadron Increased risk of gastrointestinal ulcer or bleeding Details Loxoprofen Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of gastrointestinal ulcer or bleeding Details Loxoprofen Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of bleeding Details Loxoprofen Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of bleeding Details Loxoprofen Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of bleeding Details Loxoprofen Diclofenac Transdermal Patch Flector Increased risk of bleeding Details Loxoprofen Digoxin Cardoxin® Increased digoxin exposure and prolonged half-life of digoxin Details Loxoprofen Dipyridamole Permole® An increased risk of bleeding Details Loxoprofen Edoxaban Savaysa An increased risk of bleeding Details Loxoprofen Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Loxoprofen Enoxaparin Lovenox An increased risk of bleeding Details Loxoprofen Enoxaparin Injection Lovenox An increased risk of bleeding Details Loxoprofen Epoprostenol Flolan An increased risk of bleeding Details Loxoprofen Etodolac Lodine Increased risk of bleeding Details Loxoprofen Fenoprofen Fenopron Increased risk of bleeding Details Loxoprofen Flurbiprofen Ansaid Increased risk of bleeding Details Loxoprofen Flurbiprofen Ophthalmic Ocufen Increased risk of bleeding Details Loxoprofen Fondaparinux Arixtra An increased risk of bleeding Details Loxoprofen Fondaparinux Injection Arixtra An increased risk of bleeding Details Loxoprofen Furosemide Injection Disal Reduced diuretic effectiveness and possible nephrotoxicity Details Loxoprofen Heparin An increased risk of bleeding Details Loxoprofen Heparin Injection Lipo-Hepin® An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.