Magnesium Trisilicate

Name: Magnesium Trisilicate Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

52 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mefenamic Acid Neratinib Octreotide Injection Hydroxychloroquine Erdafitinib Infigratinib

14 Major 30 Moderate 8 Minor

All (52) Major (14) Moderate (30) Minor (8)

Minor

Magnesium Trisilicate Azithromycin AzaSite Reduced azithromycin exposure Details Magnesium Trisilicate Alendronate Binosto Decreased alendronate absorption Details Magnesium Trisilicate Bisacodyl Alophen Reformulated Jan 2008 Decreased effectiveness of bisacodyl Details Magnesium Trisilicate Bisacodyl Rectal Bisac-Evac Decreased effectiveness of bisacodyl Details Magnesium Trisilicate Didanosine Videx® An increased risk of adverse effects from the antacid Details Magnesium Trisilicate Etidronate Didronel® Decreased etidronate absorption Details Magnesium Trisilicate Glipizide Glucotrol Hypoglycemia (CNS depression, seizures) Details Magnesium Trisilicate Naproxen Aleve Delayed absorption of naproxen Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.