Meclofenamate

290 interactions 246 cited references
Also sold as: Meclodium® Meclomen®
About Meclofenamate

Meclofenamate is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). It is also used to relieve other types of mild to moderate pain, includin… Read the full Meclofenamate drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Moderate

Meclofenamate Lisinopril Prinivil Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Atenolol Tenormin Reduced antihypertensive effect Details Meclofenamate Acebutolol Sectral® Reduced antihypertensive effect Details Meclofenamate Benazepril Lotensin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Azilsartan Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Betaxolol Betoptic S Reduced antihypertensive effect Details Meclofenamate Betaxolol Ophthalmic Betoptic® Reduced antihypertensive effect Details Meclofenamate Bisoprolol Zebeta® Reduced antihypertensive effect Details Meclofenamate Captopril Capoten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Desmopressin Nasal Concentraid® Increased risk of water intoxication with hyponatremia Details Meclofenamate Enalapril Epaned Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Eprosartan Teveten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Esmolol Brevibloc Reduced antihypertensive effect Details Meclofenamate Fosinopril Monopril® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Irbesartan Avapro Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Labetalol Normodyne® Reduced antihypertensive effect Details Meclofenamate Levobunolol Ophthalmic AKBeta® Reduced antihypertensive effect Details Meclofenamate Levofloxacin Levaquin An increased risk of seizures Details Meclofenamate Levofloxacin Injection Levaquin An increased risk of seizures Details Meclofenamate Levothyroxine Ermeza Transient increase in FT4 followed by decrease in serum T4 and normal FT4 and TSH levels Details Meclofenamate Losartan Arbli Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Anisindione An increased risk of bleeding Details Meclofenamate Azilsartan Medoxomil Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Candesartan Atacand Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Carteolol Reduced antihypertensive effect Details Meclofenamate Carvedilol Coreg Reduced antihypertensive effect Details Meclofenamate Celiprolol Reduced antihypertensive effect Details Meclofenamate Ciprofloxacin An increased risk of convulsions Details Meclofenamate Desmopressin DDAVP Increased risk of water intoxication with hyponatremia Details Meclofenamate Dicumarol An increased risk of bleeding Details Meclofenamate Enalaprilat Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Ginkgo An increased risk of bleeding Details Meclofenamate Levobunolol Betagan Reduced antihypertensive effect Details Meclofenamate L-Methylfolate Decreased l-methylfolate efficacy Details Meclofenamate Ma Huang Increased risk of developing gastric mucosal lesions Details Meclofenamate Metipranolol Reduced antihypertensive effect Details Meclofenamate Metoprolol Kapspargo Reduced antihypertensive effect Details Meclofenamate Moexipril Univasc® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Meclofenamate Nadolol Corgard Reduced antihypertensive effect Details Meclofenamate Nebivolol Bystolic Reduced antihypertensive effect Details

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