Metoclopramide Nasal Spray

247 interactions 689 cited references

Also sold as: Gimoti Gimoti®

About Metoclopramide Nasal Spray

Metoclopramide nasal spray is used to relieve symptoms caused by slow stomach emptying in people who have diabetes. These symptoms include nausea, vomiting, heartburn, loss of appetite, and feeling of fullness that lasts long after meals. Metoclopramide is in a class of medications called prokinetic agents. It works by… Read the full Metoclopramide Nasal Spray drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Iloperidone Imipramine Levomilnacipran Loxapine Zuclopenthixol Mavorixafor

63 Contraindicated 174 Major 6 Moderate 4 Minor

All (247) Contraindicated (63) Major (174) Moderate (6) Minor (4)

Contraindicated

Metoclopramide Nasal Spray Amineptine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Amitriptyline Elavil An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Amitriptylinoxide An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Amoxapine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Aripiprazole Abilify An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Aripiprazole Lauroxil Aristada An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Asenapine Saphris An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Brexpiprazole Rexulti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Cariprazine Vraylar An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Chlorpromazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Chlorprothixene An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Citalopram Celexa An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Clomipramine Anafranil An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Clozapine Clozaril An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Desipramine Norpramin An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Desvenlafaxine Pristiq An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Dibenzepin An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Doxepin Prudoxin An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Duloxetine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Escitalopram Lexapro An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Fluphenazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Fluvoxamine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Haloperidol An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Iloperidone Fanapt An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Imipramine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Levomilnacipran An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Loxapine Adasuve An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Lurasidone Latuda An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Mavorixafor Xolremdi Increased CYP2D6 substrate exposure and an increased risk of CYP2D6 substrate-related adverse events Details Metoclopramide Nasal Spray Melitracen An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Mesoridazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Methotrimeprazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Milnacipran Savella An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Molindone An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Nefazodone An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Nortriptyline An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Olanzapine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Opipramol An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Paliperidone Erzofri An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Nasal Spray Periciazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.