Ozanimod

86 interactions 6 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acetaminophen And Codeine Methyldopa Methylphenidate Transdermal Patch Morphine Injection Methylphenidate Maprotiline
8 Contraindicated 70 Major 8 Moderate
All (86) Contraindicated (8) Major (70) Moderate (8)

Major

Ozanimod Granisetron Injection Granisol Additive effects on heart rate Details Ozanimod Histrelin Implant Supprelin Additive effects on heart rate Details Ozanimod Hydromorphone Injection Dilaudid Increased risk of serious adverse reactions Details Ozanimod Hydromorphone Rectal available generically Increased risk of serious adverse reactions Details Ozanimod Hydroxychloroquine Plaquenil Additive effects on heart rate Details Ozanimod Inotuzumab Ozogamicin Injection Besponsa Additive effects on heart rate Details Ozanimod Ivabradine Corlanor Additive effects on heart rate Details Ozanimod Ketoconazole Topical Extina® Foam Additive effects on heart rate Details Ozanimod Leniolisib Joenja Increased BCRP substrate exposure Details Ozanimod Lenvatinib Lenvima Additive effects on heart rate Details Ozanimod Levodopa Oral Inhalation Inbrija Increased risk of levodopa adverse effects, including severe orthostatic hypotension Details Ozanimod Levofloxacin Levaquin Additive effects on heart rate Details Ozanimod Levofloxacin Injection Levaquin Additive effects on heart rate Details Ozanimod Mefloquine Lariam® Additive effects on heart rate Details Ozanimod Metronidazole Flagyl Additive effects on heart rate Details Ozanimod Metronidazole Injection Flagyl Additive effects on heart rate Details Ozanimod Metronidazole Topical MetroCream® Additive effects on heart rate Details Ozanimod Metronidazole Vaginal MetroGel® Vaginal Additive effects on heart rate Details Ozanimod Midostaurin Rydapt Increased BCRP substrate exposure Details Ozanimod Moxifloxacin Avelox Additive effects on heart rate Details Ozanimod Moxifloxacin Injection Avelox Additive effects on heart rate Details Ozanimod Moxifloxacin Ophthalmic Moxeza® Additive effects on heart rate Details Ozanimod Nafarelin Nasal Spray Synarel Additive effects on heart rate Details Ozanimod Nalbuphine Injection Nubain® Increased risk of serious adverse reactions Details Ozanimod Octreotide Bynfezia Additive effects on heart rate Details Ozanimod Octreotide Injection Bynfezia Additive effects on heart rate Details Ozanimod Ofloxacin Floxin® Additive effects on heart rate Details Ozanimod Ofloxacin Ophthalmic Ocuflox Additive effects on heart rate Details Ozanimod Ofloxacin Otic Floxin® Otic Additive effects on heart rate Details Ozanimod Olodaterol Oral Inhalation Striverdi Potentiated cardiovascular effects Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.